Key facts about Clonidine
What dosages is Clonidine available in?
Clonidine is available as a 0.1 mg, 0.2 mg, and 0.3 mg oral tablet.
What is Clonidine used for?
Clonidine is an alpha agonist used for high blood pressure.
How does Clonidine work?
Clonidine is a type of medication called alpha agonist. It works in the brain to lower the activity of stress hormones, such as norepinephrine. By doing so, Clonidine slows down your heart rate and relaxes your blood vessels. This allows for blood to easily flow throughout the body and brings down blood pressure.
How do I take Clonidine?
Clonidine is typically taken by mouth in dose ranges from 0.2 mg to 0.6 mg daily, but taken in divided doses throughout the day.
Is it safe for me to take Clonidine?
Clonidine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Clonidine Common Side Effects
Common side effects of Clonidine include:
- Dry mouth
- Drowsiness
- Dizziness
- Constipation
- Feeling low energy
Clonidine Serious Side Effects
Serious side effects are rare with Clonidine. Contact your healthcare provider immediately if you experience any of the following.
- Dangerously high blood pressure (from withdrawals): Nervousness, agitation, headache, tremor, feeling delirious, sudden confusion, trouble speaking, seizures
Effects of other drugs, drug classes and over-the-counter products on Clonidine
The following medications may interact with Clonidine:
- Clonidine may potentiate the CNS-depressive effects of alcohol, barbiturates or other sedating drugs. You may need an increase in the Clonidine dose
- Due to a potential for additive effects such as bradycardia and AV block, caution is warranted in patients receiving Clonidine concomitantly with agents known to affect sinus node function or AV nodal conduction, e.g., digitalis, calcium channel blockers and beta-blockers
Who makes Clonidine?
Various FDA-approved generic manufacturers
Is Clonidine safe in pregnancy?
It is not known if Clonidine will harm your unborn baby. If you become pregnant while receiving Clonidine, talk to your healthcare provider.













