Key facts about Clofarabine
What dosages is Clofarabine available in?
Clofarabine is available as a 20 mg/20 mL single use vial.
What is Clofarabine used for?
Clofarabine is used to treat acute lymphoblastic leukemia (ALL), a cancer of the white blood cells, in patients who have already used at least 2 other cancer medicines.
How does Clofarabine work?
Clofarabine is an antineoplastic (cancer) medicine. It interferes with the growth of cancer cells, which are eventually destroyed by the body.
How do I take Clofarabine?
You will receive this medicine while you or your child are in a hospital or cancer treatment center. A doctor or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins. The medicine is usually given every day for 5 days. Each treatment usually takes about 2 hours.
Is it safe for me to take Clofarabine?
Clofarabine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Clofarabine Common Side Effects
Common side effects of Clofarabine:
- Nausea
- Vomiting
- Diarrhea
- Febrile neutropenia
- Headache
- Rash
- Itching
- Fever
- Fatigue
- Anxiety
- Flushing
Clofarabine Serious Side Effects
Serious side effects are rare with Clofarabine. This medication may increase your risk to bruise or bleed. Call your care team if you notice any unusual bleeding. This medication may increase your risk of getting an infection. Call your care team for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu.
This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your care team right away if you notice fevers or flu-like symptoms with a rash.
Effects of other drugs, drug classes and over-the-counter products on Clofarabine
- There are no major drug interactions listed for Clofarabine. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes Clofarabine?
Various FDA-approved generic manufacturers
Is Clofarabine safe in pregnancy?
Clofarabine may cause fetal harm when administered to a pregnant woman. Women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Clofarabine. All patients should be advised to use effective contraceptive measures to prevent pregnancy.













