Key facts about Ceftolozane/Tazobactam
What dosages is Ceftolozane/Tazobactam available in?
Ceftolozane/Tazobactam is available as an IV injection that contains ceftolozane 1 g (equivalent to 1.147 g ceftolozane sulfate) and tazobactam 0.5 g (equivalent to 0.537 g tazobactam
sodium.
What is Ceftolozane/Tazobactam used for?
Ceftolozane/Tazobactam is an antibiotic and is used for the following:
- Severe stomach infections, when used together with metronidazole (Flagyl)
- Severe urinary tract infections (UTIs)
- Pneumonia that develops when you’re hospitalized or when you’re on a ventilator
How does Ceftolozane/Tazobactam work?
Ceftolozane/Tazobactam is typically used to treat 1) severe stomach infections, when used together with metronidazole (Flagyl); 2) severe urinary tract infections (UTIs); and 3) pneumonia that develops when you’re hospitalized or when you’re on a ventilator.
How do I take Ceftolozane/Tazobactam?
Ceftolozane/Tazobactam is typically dosed every 8 hours by intravenous
infusion over 1 hour in adult and pediatric patients. Your dose will depend on the infection being treated.
Is it safe for me to take Ceftolozane/Tazobactam?
Ceftolozane/Tazobactam is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Ceftolozane/Tazobactam is contraindicated in patients with known serious
hypersensitivity to the components of Ceftolozane/Tazobactam (ceftolozane and tazobactam), piperacillin/tazobactam, or other members of the beta-lactam class.
Ceftolozane/Tazobactam Common Side Effects
Common side effects of Ceftolozane/Tazobactam:
- Nausea
- Diarrhea
- Headache
- Fever
- Stomach pain
Ceftolozane/Tazobactam Serious Side Effects
Serious side effects are rare with Ceftolozane/Tazobactam.
Effects of other drugs, drug classes and over-the-counter products on Ceftolozane/Tazobactam
There are no major drug interactions listed for Ceftolozane/Tazobactam. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Ceftolozane/Tazobactam?
Various FDA-approved generic manufacturers
Is Ceftolozane/Tazobactam safe in pregnancy?
It is not known if Ceftolozane/Tazobactam can harm your unborn baby. Ceftolozane/Tazobactam should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.
