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MEDICAL INFORMATION
Zerbaxa Key Facts
What is Zerbaxa?
Zerbaxa is the brand name for ceftolozane and tazobactam and is available as an injection for IV use.
What dosages is Zerbaxa available in?
Zerbaxa is available as an IV injection that contains ceftolozane 1 g (equivalent to 1.147 g ceftolozane sulfate) and tazobactam 0.5 g (equivalent to 0.537 g tazobactam
sodium.
What is Zerbaxa used for?
Zerbaxa is an antibiotic and is used for the following:
- Severe stomach infections, when used together with metronidazole (Flagyl)
- Severe urinary tract infections (UTIs)
- Pneumonia that develops when you’re hospitalized or when you’re on a ventilator
How does Zerbaxa work?
Zerbaxa is typically used to treat 1) severe stomach infections, when used together with metronidazole (Flagyl); 2) severe urinary tract infections (UTIs); and 3) pneumonia that develops when you’re hospitalized or when you’re on a ventilator.
How do I take Zerbaxa?
Zerbaxa is typically dosed every 8 hours by intravenous
infusion over 1 hour in adult and pediatric patients. Your dose will depend on the infection being treated.
Is it safe for me to take Zerbaxa?
Zerbaxa is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Zerbaxa is contraindicated in patients with known serious
hypersensitivity to the components of Zerbaxa (ceftolozane and tazobactam), piperacillin/tazobactam, or other members of the beta-lactam class.
Zerbaxa Common Side Effects
Common side effects of Zerbaxa:
- Nausea
- Diarrhea
- Headache
- Fever
- Stomach pain
Zerbaxa Serious Side Effects
Serious side effects are rare with Zerbaxa.
Effects of other drugs, drug classes and over-the-counter products on Zerbaxa
There are no major drug interactions listed for Zerbaxa. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Zerbaxa?
Merck & Co., Inc.
Is Zerbaxa safe in pregnancy?
It is not known if Zerbaxa can harm your unborn baby. Zerbaxa should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.
What is the generic name for Zerbaxa?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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We are a broad skilled and passionate group of clinicians with experience of operating in health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do. You can read more about our medical team by visiting the medical team page or learn more about how we curate content by visiting our editorial process
Jamie Winn
US Board Certified Pharmacist
Monica Khosla
Medical Writer
Aseel Hamoud Bedan
Hospital Consultant
Daniel Cheung
Pharmacist Independent Prescriber, Pharmacist
Navin Khosla
UK Responsible Person (UKRP), Pharmacist Independent Prescriber, Clinical Safety Officer (CSO), Pharmacist
Ihtesham Sabri
Medical Director
Ketan Patel
Pharmacist Independent Prescriber, Pharmacist
Stefano Mirabello
Pharmacist Independent Prescriber, Clinical Safety Officer (CSO), Pharmacist
Amish Patel
Pharmacist Independent Prescriber, Superintendant Pharmacist, Pharmacist
Rajive Patel
Medical Writer
DeLon Canterbury
US Board Certified Pharmacist/PGX & Deprescribing Specialist