Key facts about Cefepime/Enmetazobactam
What dosages is Cefepime/Enmetazobactam available in?
Cefepime/Enmetazobactam is available as a sterile powder for reconstitution in single-dose vials containing 2 grams cefepime and 0.5 grams enmetazobactam.
What is Cefepime/Enmetazobactam used for?
Cefepime/Enmetazobactam is a cephalosporin antibiotic/beta lactamase inhibitor combinations are used to treat complicated bacterial infections like intra-abdominal infections and urinary tract infections.
How does Cefepime/Enmetazobactam work?
Cefepime/Enmetazobactam is a cephalosporin antibiotic that prevents the growth of the bacteria, and the beta lactamase inhibitor protects the antibiotic from the bacteria, increasing the effectiveness.
How do I take Cefepime/Enmetazobactam?
Cefepime/Enmetazobactam is given as 2.5 grams (2 grams cefepime and 0.5 grams enmetazobactam) every 8 hours by intravenous infusion over 2 hours for 7 days to 14 days, in patients 18 years of age and older with an estimated glomerular filtration rate (eGFR) between 60 to 129 mL/min. Your dose will be decreased if you have kidney impairment.
Is it safe for me to take Cefepime/Enmetazobactam?
Cefepime/Enmetazobactam is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you are allergic to the components of Cefepime/Enmetazobactam (cefepime and enmetazobactam), or other beta-lactam antibacterial drugs.
Cefepime/Enmetazobactam Common Side Effects
Common side effects of Cefepime/Enmetazobactam: Increased liver enzymes Headache Increased bilirubin Infusion site reactions.
Cefepime/Enmetazobactam Serious Side Effects
Serious side effects are rare with Cefepime/Enmetazobactam. Contact your healthcare provider immediately if you experience any of the following: Allergic reactions Clostridioides difficile-associated diarrhea.
Effects of other drugs, drug classes and over-the-counter products on Cefepime/Enmetazobactam
The following medications may interact with Exblifeb: Aminoglycosides/diuretics: Monitor kidney function if aminoglycosides are to be administered with Exblifeb.
Who makes Cefepime/Enmetazobactam?
Various FDA-approved generic manufacturers
Is Cefepime/Enmetazobactam safe in pregnancy?
It is not known whether Ezblifeb will harm your unborn baby. Talk with your healthcare provider about the risks of taking this medication if you are pregnant or plan on becoming pregnant.
