capivasertib
Used for Cancer
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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capivasertib Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is capivasertib available in?
capivasertib is available as a 160 mg and 200 mg oral tablet.
What is capivasertib used for?
capivasertib is a kinase inhibitor indicated, in combination with fulvestrant for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer with one or more PIK3CA/AKT1/PTEN-alterations as
detected by an FDA-approved test following progression on at least one endocrine-based regimen in the metastatic setting or recurrence on or within 12 months of completing adjuvant therapy.
How does capivasertib work?
capivasertib works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.
How do I take capivasertib?
The recommended dose of capivasertib is 400 mg orally twice daily, with or without food, for 4 days followed by 3 days off.
Is it safe for me to take capivasertib?
capivasertib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
capivasertib Common Side Effects
Common side effects of capivasertib:
- Diarrhea
- Skin reactions
- Increased blood sugars
- Decreased lymphocytes
- Decreased hemoglobin
- Nausea
- Fatigue
- Decreased leukocytes
- Increased triglycerides
- Decreased neutrophils
- Increased creatinine
- Vomiting
capivasertib Serious Side Effects
Serious side effects are rare with capivasertib. Let your doctor know right away if you experience any of the following.
- High blood sugar levels (hyperglycemia)
- Severe diarrhea
- Skin reactions
Effects of other drugs, drug classes and over-the-counter products on capivasertib
The following medications may interact with capivasertib:
- Strong CYP3A Inhibitors: Avoid concomitant use. If concomitant use cannot be avoided, reduce capivasertib dose.
- Moderate CYP3A Inhibitors: Reduce capivasertib dose
- Strong and Moderate CYP3A Inducers: Avoid concomitant use
Who makes capivasertib?
Various FDA-approved generic manufacturers
Is capivasertib safe in pregnancy?
capivasertib can harm your unborn baby. Females who are able to become pregnant:
- Your healthcare provider will check to see if you are pregnant before you start treatment with capivasertib
- You should use effective birth control during treatment with capivasertib and for 1 month after the last dose
- Talk to your healthcare provider about birth control methods that may be right for you during this time.
If you become pregnant or think you are pregnant, tell your healthcare provider right away - Males with female partners who are able to become pregnant should use effective birth control during your treatment with capivasertib and for 4 months after the last dose. If your female partner becomes pregnant, tell your healthcare provider right away
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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