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Aptivus is the brand name for tipranavir and is available as an oral capsule and solution.

Aptivus is available as a 250 mg oral capsule and a 100 mg/ml oral solution.

Aptivus is a HIV ARV and is used for HIV treatment.

Aptivus is a protease (an enzyme) inhibitor (PI). Normally, protease helps process viral proteins so the HIV virus can infect healthy cells. When protease is stopped by PI medications, the HIV virus cannot make copies of itself and infect your cells.

Aptivus is typically taken as 500 mg with ritonavir 200 mg twice daily for adults.

• Children: The typical dose is based on the child’s weight, but won’t be more than the adult dose

Aptivus is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have moderate or severe (Child-Pugh Class B or C) hepatic impairment. Use drugs highly dependent on CYP 3A for clearance or are potent CYP 3A inducers.

Common side effects of Aptivus:

• Diarrhea
• Nausea
• Fever
• Vomiting
• Fatigue
• Headache

Serious side effects are rare with Aptivus.

The following medications may interact with Aptivus:

• Co-administration of Aptivus can alter the concentrations of other drugs and other drugs may alter the concentration of tipranavir. The potential for drug-drug interactions must be considered prior to and during therapy

Boehringer Ingelheim Pharmaceuticals, Inc.

There are no adequate and well-controlled studies in pregnant women for the treatment of HIV-1 infection. Aptivus should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

• Tipranavir