Key facts about Aprocitentan
What dosages is Aprocitentan available in?
Aprocitentan is available as a 12.5 mg oral tablet.
What is Aprocitentan used for?
Aprocitentan is an endothelin receptor antagonist indicated for the treatment of hypertension in combination with other antihypertensive medications to lower blood pressure in adult patients who are not adequately controlled on other drugs.
How does Aprocitentan work?
Aprocitentan is an endothelin receptor antagonist (ERA). It blocks the action of endothelin-1, a substance in the body that narrows the blood vessels and causes high blood pressure. Blocking the action of this substance relaxes the blood vessels in the body, which lead to lower blood pressure and easier blood flow to the heart.
How do I take Aprocitentan?
Aprocitentan is given as 12.5 mg by mouth once daily, with or without food.
Is it safe for me to take Aprocitentan?
Aprocitentan is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you are pregnant or are allergic to Aprocitentan or any inactive ingredients in the product.
Aprocitentan Common Side Effects
Common side effects of Aprocitentan: Edema (fluid build up in the body, swelling) Anemia
Aprocitentan Serious Side Effects
Serious side effects are rare with Aprocitentan. Contact your healthcare provider immediately if you experience any of the following: Fluid build up in the body: shortness of breath; swelling in the legs, ankles, or feet; irregular heartbeat; chest pain; not able to exercise; tiredness; unusual weight gain Liver injury: loss of appetite, nausea, vomiting, stomach pain in the upper right side, dark urine, fever, yellowing of the skin or whites of the eyes Anemia (low red blood cell count): tiredness, shortness of breath, irregular heartbeat, dizziness, chest pain, pale skin Allergic reaction: rash, red skin, swelling
Effects of other drugs, drug classes and over-the-counter products on Aprocitentan
There are no drug interactions listed for Aprocitentan.
Who makes Aprocitentan?
Various FDA-approved generic manufacturers
Is Aprocitentan safe in pregnancy?
Based on animal reproduction studies with other ERAs, Aprocitentan can cause harm to your unborn baby, including birth defects and fetal death. Because of this Aprocitentan is contraindicated during pregnancy
