Save on Aprocitentan with Coupons, Discounts & Savings Programs

Aprocitentan is available as a 12.5 mg oral tablet.

Aprocitentan is an endothelin receptor antagonist indicated for the treatment of hypertension in combination with other antihypertensive medications to lower blood pressure in adult patients who are not adequately controlled on other drugs.

Aprocitentan is an endothelin receptor antagonist (ERA). It blocks the action of endothelin-1, a substance in the body that narrows the blood vessels and causes high blood pressure. Blocking the action of this substance relaxes the blood vessels in the body, which lead to lower blood pressure and easier blood flow to the heart.

Aprocitentan is given as 12.5 mg by mouth once daily, with or without food.

Aprocitentan is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you are pregnant or are allergic to Aprocitentan or any inactive ingredients in the product.

Common side effects of Aprocitentan: Edema (fluid build up in the body, swelling) Anemia

Serious side effects are rare with Aprocitentan. Contact your healthcare provider immediately if you experience any of the following: Fluid build up in the body: shortness of breath; swelling in the legs, ankles, or feet; irregular heartbeat; chest pain; not able to exercise; tiredness; unusual weight gain Liver injury: loss of appetite, nausea, vomiting, stomach pain in the upper right side, dark urine, fever, yellowing of the skin or whites of the eyes Anemia (low red blood cell count): tiredness, shortness of breath, irregular heartbeat, dizziness, chest pain, pale skin Allergic reaction: rash, red skin, swelling

There are no drug interactions listed for Aprocitentan.

Various FDA-approved generic manufacturers

Based on animal reproduction studies with other ERAs, Aprocitentan can cause harm to your unborn baby, including birth defects and fetal death. Because of this Aprocitentan is contraindicated during pregnancy

• Tryvio