How can I lower the cost of my amivantamab-vmjw

You can lower cost of your amivantamab-vmjw using one of the 4 following drug savings programs: Rx Advantage Card for amivantamab-vmjw, Canadian Prescription Savings for amivantamab-vmjw, amivantamab-vmjw Drug Coupons, amivantamab-vmjw Patient Assistance Programs

amivantamab-vmjw Coupon, Savings Card and Patient Assistance

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amivantamab-vmjw

Used for Cancer

Are you tired of high medication costs? Our service offers unbeatable savings on your amivantamab-vmjw prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.

Manufactured by various FDA-approved generic manufacturers.

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

This content is intended for US audiences only

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amivantamab-vmjw Uses, Side Effects, Interactions, Warnings & Dosing

Medically reviewed by Navin Khosla, B.Pharm

Written by Rajive Patel, B.Pharm

What dosages is amivantamab-vmjw available in?

amivantamab-vmjw is available as a 350 mg/7 mL (50 mg/mL) solution that is an injection for IV use.

What is amivantamab-vmjw used for?

amivantamab-vmjw is an EGFR and MET inhibitor that is used to treat:

Locally advanced or metastatic non-small cell lung cancer (NSCLC) with EGFR exon 20 insertion mutations in people who have previously received platinum-based chemotherapy

How does amivantamab-vmjw work?

amivantamab-vmjw is an EGFR and MET inhibitor. It’s a bispecific monoclonal antibody that targets proteins on tumor cells called EGFR and MET. MET and EGFR are proteins in the body involved in signaling cells to grow and divide.

In certain lung cancers, mutations (changes) in specific genes lead to abnormal MET and EGFR proteins. This causes cells to grow out of control. amivantamab-vmjw works by attaching (binding) to EGFR and MET proteins, blocking the tumor from growing, and alerting the immune system to destroy those abnormal cells.

How do I take amivantamab-vmjw?

amivantamab-vmjw is given as an intravenous (IV) infusion. The typical dose of amivantamab-vmjw depends on your weight:

Weight less than 80 kg (176 lbs): The recommended dose is 1050 mg
Weight 80 kg (176 lbs) or more: The recommended dose is 1400 mg
The dosing schedule for amivantamab-vmjw is in 28-day cycles
During your first cycle, you’ll receive an infusion on days 1 and 2, then weekly on day 8, day 15, and day 22.
After your first cycle, you’ll get the infusion every other week (day 1 and day 15 of each cycle)

Is it safe for me to take amivantamab-vmjw?

amivantamab-vmjw is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

amivantamab-vmjw Common Side Effects

Common side effects of amivantamab-vmjw:

Rash
Infusion reaction (e.g., trouble breathing, chills, nausea)
Nail infection
Muscle, bone, or joint pain
Shortness of breath
Nausea
Fatigue
Swelling
Mouth sores
Cough
Constipation
Vomiting

amivantamab-vmjw Serious Side Effects

Serious side effects are rare with amivantamab-vmjw. Contact your healthcare provider immediately if you experience any of the following.

Infusion reactions: hives, breathing problems, dizziness, chills, chest pain, swelling of the mouth or lips
Lung damage: cough, shortness of breath, fever
Severe skin reactions: burning, redness, rashes, blisters, or peeling
Eye problems: eye pain, redness, dryness, or itching; vision changes

Effects of other drugs, drug classes and over-the-counter products on amivantamab-vmjw

There are no major drug interactions listed for amivantamab-vmjw. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking

Who makes amivantamab-vmjw?

Various FDA-approved generic manufacturers

Is amivantamab-vmjw safe in pregnancy?

Based on its mechanism of action and findings from animal models, amivantamab-vmjw can cause fetal harm when administered to a pregnant woman. If you can become pregnant, you should to use effective contraception during treatment and for 3 months after the last dose of amivantamab-vmjw.

What is the brand name for amivantamab-vmjw?

RYBREVANT

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects

Drug Savings Tips

How can NowPatient help me to lower the cost of my amivantamab-vmjw prescription?

How do the NowPatient amivantamab-vmjw savings programs work?

Are the NowPatient amivantamab-vmjw savings programs suitable for everyone, regardless of insurance status?

	Rx Advantage Card* for amivantamab-vmjw	Canadian Prescription Savings* for amivantamab-vmjw	amivantamab-vmjw Drug Coupon*	amivantamab-vmjw Patient Assistance Program*
Insured (federal, state or government)	Available	Available	Not Available	Available If Offered by Pharmaceutical Company
Insured (Commercial or Private)	Available	Available	Available If Offered by Pharmaceutical Company	Available If Offered by Pharmaceutical Company
Uninsured	Available	Available	Not Available	Available If Offered by Pharmaceutical Company
Insured but without pharmacy benefit or drug coverage	Available	Available	Not Available	Available If Offered by Pharmaceutical Company

Are the NowPatient drug savings programs suitable for brand and generic versions of amivantamab-vmjw?

	Rx Advantage Card* for amivantamab-vmjw	Canadian Prescription Savings* for amivantamab-vmjw	amivantamab-vmjw Drug Coupon*	amivantamab-vmjw Patient Assistance Program*
Brand	Yes	Yes	Yes, If Offered by Pharmaceutical Company	Yes, If Offered by Pharmaceutical Company
Generic	Yes	Yes	No	No

If you have Medicare Part D or Medicare Advantage and none of the amivantamab-vmjw savings options are applicable or affordable for me, what can you do?

I am uninsured or underinsured and none of the amivantamab-vmjw prescription saving options are applicable or affordable for me, what can I do?

I am commercially or privately insured and none of the amivantamab-vmjw prescription saving options are applicable or affordable for me, what can I do?

If I have federal, state or commercial insurance and none of the amivantamab-vmjw prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?

If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:

1. Patient Access Network Foundation (PAN) assistance for amivantamab-vmjw

If you are having trouble paying for your amivantamab-vmjw medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for amivantamab-vmjw you will need to meet one or all of the following criteria:

Your income is below 400% of the federal poverty level
amivantamab-vmjw is prescribed for an approved FDA indication
You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
You have Medicare insurance coverage that covers amivantamab-vmjw
If amivantamab-vmjw is listed on PAN’s list of covered medications

You can check the Patient Access Network Foundation Website for more information.

2. HealthWell Foundation Copay Program for amivantamab-vmjw

If you are having trouble paying for your amivantamab-vmjw medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for amivantamab-vmjw you will need to meet the following criteria:

You live in and are being treated in the United States
You are insured and your plan covers amivantamab-vmjw
If amivantamab-vmjw is listed on the HealthWell Foundation’s list of covered medications

You can check the HealthWell Foundation Website for more information.

3. Patient Advocate Foundation Co-Pay Relief Program for amivantamab-vmjw

Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your amivantamab-vmjw treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for amivantamab-vmjw you will need to meet the following criteria:

You must be currently insured and have coverage for amivantamab-vmjw
You must have a confirmed diagnosis and treatment plan
You must reside and receive treatment in the United States
Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.

You can check the Patient Advocate Foundation Website for more information.

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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