Used for Cancer

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Programs are suitable for individuals who want to buy amivantamab-vmjw without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by various FDA-approved generic manufacturers.

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Updated on 24 Apr 2024

Learn more about amivantamab-vmjw

What dosages is amivantamab-vmjw available in?

What dosages is amivantamab-vmjw available in?

amivantamab-vmjw is available as a 350 mg/7 mL (50 mg/mL) solution that is an injection for IV use.

What is amivantamab-vmjw used for?

What is amivantamab-vmjw used for?

amivantamab-vmjw is an EGFR and MET inhibitor that is used to treat:

  • Locally advanced or metastatic non-small cell lung cancer (NSCLC) with EGFR exon 20 insertion mutations in people who have previously received platinum-based chemotherapy
How does amivantamab-vmjw work?

How does amivantamab-vmjw work?

amivantamab-vmjw is an EGFR and MET inhibitor. It’s a bispecific monoclonal antibody that targets proteins on tumor cells called EGFR and MET. MET and EGFR are proteins in the body involved in signaling cells to grow and divide.

In certain lung cancers, mutations (changes) in specific genes lead to abnormal MET and EGFR proteins. This causes cells to grow out of control. amivantamab-vmjw works by attaching (binding) to EGFR and MET proteins, blocking the tumor from growing, and alerting the immune system to destroy those abnormal cells.

How do I take amivantamab-vmjw?

How do I take amivantamab-vmjw?

amivantamab-vmjw is given as an intravenous (IV) infusion. The typical dose of amivantamab-vmjw depends on your weight:

  • Weight less than 80 kg (176 lbs): The recommended dose is 1050 mg
  • Weight 80 kg (176 lbs) or more: The recommended dose is 1400 mg
  • The dosing schedule for amivantamab-vmjw is in 28-day cycles
  • During your first cycle, you’ll receive an infusion on days 1 and 2, then weekly on day 8, day 15, and day 22.
  • After your first cycle, you’ll get the infusion every other week (day 1 and day 15 of each cycle)
Is it safe for me to take amivantamab-vmjw?

Is it safe for me to take amivantamab-vmjw?

amivantamab-vmjw is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

amivantamab-vmjw Common Side Effects

amivantamab-vmjw Common Side Effects

Common side effects of amivantamab-vmjw:

  • Rash
  • Infusion reaction (e.g., trouble breathing, chills, nausea)
  • Nail infection
  • Muscle, bone, or joint pain
  • Shortness of breath
  • Nausea
  • Fatigue
  • Swelling
  • Mouth sores
  • Cough
  • Constipation
  • Vomiting
amivantamab-vmjw Serious Side Effects

amivantamab-vmjw Serious Side Effects

Serious side effects are rare with amivantamab-vmjw. Contact your healthcare provider immediately if you experience any of the following.

  • Infusion reactions: hives, breathing problems, dizziness, chills, chest pain, swelling of the mouth or lips
  • Lung damage: cough, shortness of breath, fever
  • Severe skin reactions: burning, redness, rashes, blisters, or peeling
  • Eye problems: eye pain, redness, dryness, or itching; vision changes
Effects of other drugs, drug classes and over-the-counter products on amivantamab-vmjw

Effects of other drugs, drug classes and over-the-counter products on amivantamab-vmjw

  • There are no major drug interactions listed for amivantamab-vmjw. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes amivantamab-vmjw?

Who makes amivantamab-vmjw?

Various FDA-approved generic manufacturers

Is amivantamab-vmjw safe in pregnancy?

Is amivantamab-vmjw safe in pregnancy?

Based on its mechanism of action and findings from animal models, amivantamab-vmjw can cause fetal harm when administered to a pregnant woman. If you can become pregnant, you should to use effective contraception during treatment and for 3 months after the last dose of amivantamab-vmjw.


What to do if you missed your amivantamab-vmjw dose

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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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