ado-trastuzumab emtansine
Used for Cancer
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Manufactured by various FDA-approved generic manufacturers.
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ado-trastuzumab emtansine Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is ado-trastuzumab emtansine available in?
ado-trastuzumab emtansine is available as a single-dose vial containing 100 mg per vial or 160 mg per vial.
What is ado-trastuzumab emtansine used for?
ado-trastuzumab emtansine is used to treat HER2-positive metastatic breast cancer (cancer that has spread) in patients who have previously received other medicines (eg, trastuzumab, taxane medicine) that did not work well or whose cancer has returned during or within 6 months of completing treatment. It is also used as additional treatment in patients with HER2-positive early breast cancer who have cancer left after a taxane medicine and trastuzumab-based treatment.
How does ado-trastuzumab emtansine work?
HER2 protein is produced by some breast tumors. ado-trastuzumab emtansine interferes with the growth of this protein which also prevents tumor growth. The tumor cells will then be destroyed by the body.
How do I take ado-trastuzumab emtansine?
ado-trastuzumab emtansine is typically dosed as follows:
- 3.6 mg/kg given as an intravenous infusion every 3 weeks (21-day cycle) until disease progression or unacceptable toxicity, or a total of 14 cycles for patients with EBC. Do not administer ado-trastuzumab emtansine at doses greater than 3.6 mg/kg
Is it safe for me to take ado-trastuzumab emtansine?
ado-trastuzumab emtansine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
ado-trastuzumab emtansine Common Side Effects
Common side effects of ado-trastuzumab emtansine:
- Fatigue
- Nausea
- Joint pain
- Muscle pain
- Headache
- Nose bleeds
- Low platelet levels
- Bleeding
- Increased liver enzymes
ado-trastuzumab emtansine Serious Side Effects
Serious side effects are rare with ado-trastuzumab emtansine. Contact your healthcare provider immediately if you experience any of the following.
- Worsening breathing
- Severe bleeding
- Nerve problems
Effects of other drugs, drug classes and over-the-counter products on ado-trastuzumab emtansine
- No formal drug-drug interaction studies with ado-trastuzumab emtansine have been conducted. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes ado-trastuzumab emtansine?
Various FDA-approved generic manufacturers
Is ado-trastuzumab emtansine safe in pregnancy?
ado-trastuzumab emtansine can cause embryo-fetal harm when administered during pregnancy. Females of reproductive potential to use effective contraception during treatment with ado-trastuzumab emtansine and for 7 months following the last dose of ado-trastuzumab emtansine.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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