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MEDICAL INFORMATION
Kadcyla Key Facts
What is Kadcyla?
Kadcyla is the brand name for ado-trastuzumab emtansine IV infusion.
What dosages is Kadcyla available in?
Kadcyla is available as a single-dose vial containing 100 mg per vial or 160 mg per vial.
What is Kadcyla used for?
Kadcyla is used to treat HER2-positive metastatic breast cancer (cancer that has spread) in patients who have previously received other medicines (eg, trastuzumab, taxane medicine) that did not work well or whose cancer has returned during or within 6 months of completing treatment. It is also used as additional treatment in patients with HER2-positive early breast cancer who have cancer left after a taxane medicine and trastuzumab-based treatment.
How does Kadcyla work?
HER2 protein is produced by some breast tumors. Kadcyla interferes with the growth of this protein which also prevents tumor growth. The tumor cells will then be destroyed by the body.
How do I take Kadcyla?
Kadcyla is typically dosed as follows:
- 3.6 mg/kg given as an intravenous infusion every 3 weeks (21-day cycle) until disease progression or unacceptable toxicity, or a total of 14 cycles for patients with EBC. Do not administer Kadcyla at doses greater than 3.6 mg/kg
Is it safe for me to take Kadcyla?
Kadcyla is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Kadcyla Common Side Effects
Common side effects of Kadcyla:
- Fatigue
- Nausea
- Joint pain
- Muscle pain
- Headache
- Nose bleeds
- Low platelet levels
- Bleeding
- Increased liver enzymes
Kadcyla Serious Side Effects
Serious side effects are rare with Kadcyla. Contact your healthcare provider immediately if you experience any of the following.
- Worsening breathing
- Severe bleeding
- Nerve problems
Effects of other drugs, drug classes and over-the-counter products on Kadcyla
- No formal drug-drug interaction studies with Kadcyla have been conducted. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes Kadcyla?
Genentech, Inc.
Is Kadcyla safe in pregnancy?
Kadcyla can cause embryo-fetal harm when administered during pregnancy. Females of reproductive potential to use effective contraception during treatment with Kadcyla and for 7 months following the last dose of Kadcyla.
What is the generic name for Kadcyla?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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We are a broad skilled and passionate group of clinicians with experience of operating in health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do. You can read more about our medical team by visiting the medical team page or learn more about how we curate content by visiting our editorial process
Rajive Patel
Medical Writer
Navin Khosla
Pharmacist
Monica Khosla
Medical Writer
Ihtesham Sabri
Medical Director
Ketan Patel
Pharmacist Independent Prescriber
Jamie Winn
Pharmacist
Daniel Cheung
Pharmacist Independent Prescriber
Amish Patel
Pharmacist Independent Prescriber
DeLon Canterbury
Pharmacist
Stefano Mirabello
Pharmacist Independent Prescriber
Aseel Hamoud Bedan
Hospital Consultant