Save on Abatacept with Coupons, Discounts & Savings Programs

Abatacept is available in one of the following:

• Intravenous Infusion 250 mg lyophilized powder in a single-dose vial.

Subcutaneous Use

• 50 mg/0.4 mL, 87.5 mg/0.7 mL, 125 mg/mL solution in single-dose prefilled syringe.
  125 mg/mL solution in a single-dose prefilled ClickJect autoinjectors

Abatacept is a biologic DMARD that is used to treat:
Moderate-to-severe rheumatoid arthritis (RA) in adults
Psoriatic arthritis (PsA) in adults Moderate-to-severe polyarticular juvenile idiopathic arthritis (pJIA) in children ages 2 years and older Prevention of short-term graft versus host disease (GVHD) in combination with a calcineurin inhibitor and methotrexate in adults and children ages 2 years and older

Abatacept is a biologic disease-modifying anti-rheumatic drug (DMARD). It blocks certain proteins and processes in cells, which lowers inflammation. This prevents specific types of arthritis from getting worse.

Abatacept is dosed as follows:

• Rheumatoid arthritis and psoriatic arthritis in adults
• Intravenous (IV): Your provider will calculate the dose based on your body weight. The typical dose ranges from 500 mg to 1,000 mg infused IV every 2 weeks for 3 doses, then every month after that
• Under the skin injection: The typical dose is 125 mg injected under the skin once weekly
• Juvenile idiopathic arthritis
• Intravenous (IV): Your child’s provider will calculate tje dose based on their body weight. The typical dose is 10 mg/kg infused IV every 2 weeks for 2 doses, then every month after that. Children weighing 75 kg or more will be given the adult dose for arthritis

• Under the skin injection: Your child’s provider will calculate the dose based on your child’s body weight. The typical dose is injected under the skin once weekly
• Children weighing 10 kg to less than 25 kg: 50 mg
• Children weighing 25 kg to less than 50 kg: 87.5 mg
• Children weighing 50 kg or more: 125 mg
• Prevention graft-versus-host disease
• Your provider will calculate the dose based on your body weight and age. The typical dose ranges from 10 mg/kg to 15 mg/kg infused through the veins the day before transplant, then on Day 5, 14, and 28 after transplant.

Abatacept is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Abatacept:

• Headache
• Sore throat, runny nose, or other cold-like symptoms
• Dizziness
• Cough
• Back pain
• High blood pressure
• Upset stomach
• Pain while urinating and other symptoms of an urinary tract infection

Serious side effects are rare with Abatacept. Contact your healthcare provider immediately if you experience any of the following.

• Serious infections: fever, tiredness, chills, cough, trouble breathing
• Serious allergic reaction: hives, rash, blisters, skin reddening, swelling of the lips or tongue, difficulty breathing

The following medications may interact with Abatacept:

• Concomitant administration of a TNF antagonist with Abatacept has been associated with an increased risk of serious infections and no significant additional efficacy over use of the TNF antagonists alone. Concurrent therapy with Abatacept and TNF antagonists is not recommended

Various FDA-approved generic manufacturers

It is not known if Abatacept can harm your unborn baby. If you took Abatacept during pregnancy, talk to your healthcare provider before your baby receives any vaccines.
There is a registry for pregnant women exposed to Abatacept. The purpose of this registry is to check the health of the pregnant mother and her child. Women are encouraged to call the registry themselves or ask their healthcare provider to contact the registry for them by calling 1-877-311-8972.

• Orencia