View ZEPATIER savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or ZEPATIER Patient Assistance Program.

Programs are suitable for individuals who want to buy ZEPATIER without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by Merck & Co., Inc.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

Drug savings programs

  • Qualified

    Rx Advantage Card

    A hand holding a dark-colored prescription savings card with various ID numbers and the label "Rx Advantage." Text below states the card is not insurance and cannot be used for Medicare or Medicaid.

    Save up to 90%

  • Unavailable

    Canadian Prescription Savings

    Manufactured by
    Powered by
    Prescription Help Logo
  • Unavailable

    Drug Coupons

    A hand holds a Copay Savings Card that states eligible patients with commercial insurance may pay as little as $0 per tube for Opzelura.
  • Available

    Patient Assistance Programs

    A picture of a patient assistance application form


Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about ZEPATIER



ZEPATIER is the brand name for elbasvir and grazoprevir and is available as an oral tablet.

What dosages is ZEPATIER available in?

What dosages is ZEPATIER available in?

ZEPATIER is available as an oral tablet that contains 50 mg elbasvir and 100 mg grazoprevir.

What is ZEPATIER used for?

What is ZEPATIER used for?

ZEPATIER is an antiviral combo and is used to treat hepatitis C infection genotype 1 and 4.

How does ZEPATIER work?

How does ZEPATIER work?

ZEPATIER contains 2 antiviral medications that work together to stop the hepatitis C virus from making copies of itself in the body.

How do I take ZEPATIER?

How do I take ZEPATIER?

ZEPATIER is typically dosed at 1 tablet once a day with or without food.

Is it safe for me to take ZEPATIER?

Is it safe for me to take ZEPATIER?

ZEPATIER is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

  • Patients with moderate or severe hepatic impairment (Child-Pugh B or C)
  • OATP1B1/3 inhibitors that are known or expected to significantly increase grazoprevir plasma concentrations, strong CYP3A inducers,
    and efavirenz
  • If ZEPATIER is administered with ribavirin, the contraindications to ribavirin also apply
ZEPATIER Common Side Effects

ZEPATIER Common Side Effects

Common side effects of ZEPATIER:

  • Fatigue
  • Headache
ZEPATIER Serious Side Effects

ZEPATIER Serious Side Effects

Serious side effects are rare with ZEPATIER.

Effects of other drugs, drug classes and over-the-counter products on ZEPATIER

Effects of other drugs, drug classes and over-the-counter products on ZEPATIER

The following medications may interact with ZEPATIER:

  • Co-administration of ZEPATIER with moderate CYP3A inducers is not recommended as they may decrease the plasma concentration of ZEPATIER
  • Co-administration of ZEPATIER with certain strong CYP3A inhibitors is not recommended as they may increase the plasma concentration of ZEPATIER
  • Clearance of HCV infection with direct-acting antivirals may lead to changes in hepatic function, which may impact safe and effective use of concomitant medications. Frequent monitoring of relevant
  • laboratory parameters (INR or blood glucose) and dose adjustments of certain concomitant medications may be necessary
  • Consult the full prescribing information prior to and during treatment for potential drug interactions
Who makes ZEPATIER?

Who makes ZEPATIER?

Merck & Co., Inc.

Is ZEPATIER safe in pregnancy?

Is ZEPATIER safe in pregnancy?

No adequate human data are available to establish whether or not ZEPATIER poses a risk to pregnancy outcomes.
If ZEPATIER is administered with ribavirin, the combination regimen is contraindicated in pregnant women and in men whose female partners are pregnant. Females should avoid pregnancy during treatment and within 6 months of stopping ribavirin and to notify their healthcare provider immediately in the event of a pregnancy.


What to do if you missed your ZEPATIER dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
dollar sign

Drug Savings Tips

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

FAQ logo

People Asked

Now Patient Data Security

Data Security

Our Commitment to You.

Find out moreNow Patient Data SecurityNow Patient Data Security

What is NowPatient

Telehealth and Online Pharmacy

NowPatient is a licensed online pharmacy and doctor service that is available around the world. Our service is FREE and packed with valuable features that can benefit your health such as medication reminders, educational blogs, medically approved symptoms checker, UK NHS online pharmacyprivate treatment plansRx Advantage cardhealth conditions information, affordable medications options, genetic testinghome test kitshealth riskspollen meterair quality monitor, weight loss plans, drug savings programs and lots more!

A laptop screen displaying a health dashboard with widgets showing health profile, notifications, personalized health tools, and favorite widgets including body mass index and weight loss tracking.


To improve the lives of everyone by making high-quality care accessible and convenient

We are here to improve lives. Our service gives you access to smart features and resources that can help empower you to take control of your health and improve your health outcomes. All this, in one place, for FREE. We strive to bring a fresh perspective to managing health. NowPatient can be accessed by downloading the App or using your web browser.

Download our app today

A collage showing a map with pharmacies, a questionnaire, medication details, and a person video chatting on a screen.

Can I trust NowPatient

Meet our medical team

We are a passionate group of clinicians and medical writers covering a broad range of specialities with experience operating in health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do. You can read more about our medical team by visiting the medical team page or learn more about how we curate content by visiting our editorial process

Your Questions Answered

For your peace of mind, we can answer your questions quickly

We have a comprehensive list of FAQ’s on each feature page. Alternatively, for broader questions around our service just click the button below.
Find your answers