ZEPATIER
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Manufactured by Merck & Co., Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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ZEPATIER Uses, Side Effects, Interactions, Warnings & Dosing
What is ZEPATIER?
ZEPATIER is the brand name for elbasvir and grazoprevir and is available as an oral tablet.
What dosages is ZEPATIER available in?
ZEPATIER is available as an oral tablet that contains 50 mg elbasvir and 100 mg grazoprevir.
What is ZEPATIER used for?
ZEPATIER is an antiviral combo and is used to treat hepatitis C infection genotype 1 and 4.
How does ZEPATIER work?
ZEPATIER contains 2 antiviral medications that work together to stop the hepatitis C virus from making copies of itself in the body.
How do I take ZEPATIER?
ZEPATIER is typically dosed at 1 tablet once a day with or without food.
Is it safe for me to take ZEPATIER?
ZEPATIER is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Patients with moderate or severe hepatic impairment (Child-Pugh B or C)
- OATP1B1/3 inhibitors that are known or expected to significantly increase grazoprevir plasma concentrations, strong CYP3A inducers,
and efavirenz - If ZEPATIER is administered with ribavirin, the contraindications to ribavirin also apply
ZEPATIER Common Side Effects
Common side effects of ZEPATIER:
- Fatigue
- Headache
ZEPATIER Serious Side Effects
Serious side effects are rare with ZEPATIER.
Effects of other drugs, drug classes and over-the-counter products on ZEPATIER
The following medications may interact with ZEPATIER:
- Co-administration of ZEPATIER with moderate CYP3A inducers is not recommended as they may decrease the plasma concentration of ZEPATIER
- Co-administration of ZEPATIER with certain strong CYP3A inhibitors is not recommended as they may increase the plasma concentration of ZEPATIER
- Clearance of HCV infection with direct-acting antivirals may lead to changes in hepatic function, which may impact safe and effective use of concomitant medications. Frequent monitoring of relevant
- laboratory parameters (INR or blood glucose) and dose adjustments of certain concomitant medications may be necessary
- Consult the full prescribing information prior to and during treatment for potential drug interactions
Who makes ZEPATIER?
Merck & Co., Inc.
Is ZEPATIER safe in pregnancy?
No adequate human data are available to establish whether or not ZEPATIER poses a risk to pregnancy outcomes.
If ZEPATIER is administered with ribavirin, the combination regimen is contraindicated in pregnant women and in men whose female partners are pregnant. Females should avoid pregnancy during treatment and within 6 months of stopping ribavirin and to notify their healthcare provider immediately in the event of a pregnancy.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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