XIFAXAN
Are you tired of high medication costs? Our service offers unbeatable savings on your XIFAXAN prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by Valeant Pharmaceuticals
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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XIFAXAN key facts
What is XIFAXAN?
XIFAXAN is the brand name for rifaximin and is available as an oral tablet.
What dosages is XIFAXAN available in?
XIFAXAN is available as a 200 mg and 550 mg oral tablet.
What is XIFAXAN used for?
XIFAXAN is a rifamycin antibiotic and is used for the following:
- Treatment of travelers’ diarrhea caused by E. coli in people ages 12 years and older
- Treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults
- Prevention of hepatic encephalopathy (HE) in adults
How does XIFAXAN work?
XIFAXAN is a rifamycin antibiotic. It works by stopping bacteria from making important proteins that the bacteria need to survive. As a result, the bacteria can’t grow or spread.
How do I take XIFAXAN?
XIFAXAN is dosed as follows:
- Travelers’ diarrhea: The typical dose is 200 mg by mouth three times daily for 3 days
- Hepatic encephalopathy: The typical dose is 550 mg by mouth twice daily
- Irritable bowel syndrome with diarrhea (IBS-D): The typical dose is 550 mg by mouth three times daily for 2 weeks. If your symptoms come back after treatment, your prescriber might decide to take the medication again using the same treatment course. Your can repeat the treatment course for up to 2 times
Is it safe for me to take XIFAXAN?
XIFAXAN is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a hypersensitivity to rifaximin, rifamycin antimicrobial agents, or any of the components of XIFAXAN.
XIFAXAN Common Side Effects
Common side effects of XIFAXAN:
- Swelling in hands and feet
- Nausea
- Dizziness
- Tiredness
- Extra stomach fluid and swelling
- Headache
XIFAXAN Serious Side Effects
Serious side effects are rare with XIFAXAN. Contact your healthcare provider immediately if you experience any of the following.
- C. difficile-related diarrhea: rapid heart rate, foul-smelling diarrhea, fever, nausea, frequent bowel movements (even up to 15 times per day)
- Severe allergic reaction: rash; trouble breathing; swelling of the face, lips, tongue, or throat
Effects of other drugs, drug classes and over-the-counter products on XIFAXAN
The following medications may interact with XIFAXAN:
- Warfarin: Monitor INR and prothrombin time; dose adjustment of warfarin may be needed to maintain target INR range
Who makes XIFAXAN?
Valeant Pharmaceuticals
Is XIFAXAN safe in pregnancy?
XIFAXAN may harm your unborn baby. Tell your
healthcare provider if you are pregnant or think you are pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my XIFAXAN prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your XIFAXAN prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient XIFAXAN savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient XIFAXAN savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for XIFAXAN | Canadian Prescription Savings* for XIFAXAN | XIFAXAN Drug Coupon* | XIFAXAN Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of XIFAXAN?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for XIFAXAN | Canadian Prescription Savings* for XIFAXAN | XIFAXAN Drug Coupon* | XIFAXAN Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the XIFAXAN savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the XIFAXAN drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for XIFAXAN, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the XIFAXAN prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, XIFAXAN is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed XIFAXAN for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the XIFAXAN prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the XIFAXAN prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for XIFAXAN
If you are having trouble paying for your XIFAXAN medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for XIFAXAN you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- XIFAXAN is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers XIFAXAN
- If XIFAXAN is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for XIFAXAN
If you are having trouble paying for your XIFAXAN medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for XIFAXAN you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers XIFAXAN
- If XIFAXAN is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for XIFAXAN
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your XIFAXAN treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for XIFAXAN you will need to meet the following criteria:
- You must be currently insured and have coverage for XIFAXAN
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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Our dispensing pharmacy is regulated and authorized for internet sales by the General Pharmaceutical Council (GPhC), registration number 1036487. You can view our license credentials on the General Pharmaceutical Council website. Our superintendent pharmacist who is responsible for the safe and effective oversight of medicines supplies is Mr Amish Patel (Registration Number 2042705).
Medicines are not ordinary items of commerce. All medicines or healthcare product sales are made under the supervision of a registered pharmacist who is licensed by the GPhC. At all times, we endeavour to provide a professional and transparent service whose primary goal is to ensure that the best interests of the patient are served.
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Can you tell me more about NowPatient’s US services?
Our head of US services is Dr. Jamie Winn.
You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
We do not provide any prescribing services or dispensing services in the United States.
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