Key facts about Vyndamax
What is Vyndamax?
Vyndamax is the brand name for tafamidis and is available as an oral capsule.
What dosages is Vyndamax available in?
Vyndamax is available as an oral capsule that contains tafamidis 61 mg.
What is Vyndamax used for?
Vyndamax is a transthyretin (TTR) stabilizer that is used to treat transthyretin-mediated amyloidosis cardiomyopathy (ATTR-CM, a rare heart muscle disease).
How does Vyndamax work?
Vyndamax is a transthyretin (TTR) stabilizer. It works by attaching to a protein in your body called transthyretin. This slows protein breakdown and buildup in the heart walls, which makes it easier for the heart to pump blood to the rest of your body.
How do I take Vyndamax?
Vyndamax is typically taken as 61 mg by mouth once daily.
Is it safe for me to take Vyndamax?
Vyndamax is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Vyndamax Common Side Effects
Common side effects of Vyndamax:
- Bone, muscle, or joint problems
- Injury
- Skin problems
- Heart failure
- Falls
- Mental health problems
- Atrial fibrillation
- Shortness of breath
- Swelling of the hands, feet, or ankles
- Tiredness
- Dizziness
- Eye problems
- Constipation
Vyndamax Serious Side Effects
Serious side effects are rare with Vyndamax.
Effects of other drugs, drug classes and over-the-counter products on Vyndamax
The following medications may interact with Vyndamax:
- Coadministration of tafamidis and drugs that are BCRP substrates may increase the exposure of substrates of this transporter (e.g., methotrexate, rosuvastatin, imatinib) and the risk of the substrate-related toxicities. Monitor for signs of BCRP substrate-related toxicities and modify dosage of the substrate if appropriate
Who makes Vyndamax?
Pfizer Inc.
Is Vyndamax safe in pregnancy?
Vyndamax may harm your unborn baby. Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with VYNDAQEL or Vyndamax. You may also report your pregnancy by calling the Pfizer reporting line at 1-800-438-1985.













