VOTRIENT
Used for Cancer
Are you tired of high medication costs? Our service offers unbeatable savings on your VOTRIENT prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by Novartis Pharmaceuticals
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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VOTRIENT key facts
What is VOTRIENT?
VOTRIENT is the brand name for pazopanib and is available as an oral tablet.
What dosages is VOTRIENT available in?
VOTRIENT is available as a 200 mg oral tablet.
What is VOTRIENT used for?
VOTRIENT is a tyrosine kinase inhibitor that is used to treat:
- Advanced kidney cancer (renal cell carcinoma)
- Advanced soft tissue sarcoma, after previously receiving chemotherapy
How does VOTRIENT work?
VOTRIENT is a targeted therapy for cancer known as a tyrosine kinase inhibitor (TKI). It targets and blocks specific proteins in cancer cells called tyrosine kinases, including those in the VEGFR family, among others. These proteins are involved in providing blood supply to the tumor. By blocking these tyrosine kinases, it prevents blood vessels from forming and supplying blood to the tumor. This helps slow and stop cancer growth.
How do I take VOTRIENT?
The typical dose is 800 mg (four 200 mg tablets) by mouth once daily. Your dose might be lower if you have liver problems. During treatment, your dose can change based on how well you tolerate VOTRIENT. It might also change if you’re taking certain medications that interact with VOTRIENT.
Is it safe for me to take VOTRIENT?
VOTRIENT is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
VOTRIENT Common Side Effects
Common side effects of VOTRIENT:
- Elevated liver enzymes
- Diarrhea
- Elevated blood sugar
- High blood pressure
- Changes in hair color (e.g., lighter hair color)
- Low white blood cell levels
- Elevated bilirubin levels
- Low platelet levels
- Nausea
- Loss of appetite or not feeling hungry
- Vomiting
- Fatigue
- Low blood sugar
VOTRIENT Serious Side Effects
Serious side effects are rare with VOTRIENT. Contact your healthcare provider immediately if you experience any of the following.
- Serious infections: body aches, chills, fever, headache, new cough, sore throat, tiredness
- Serious heart problems: chest pounding, chest pain, irregular heartbeat, shortness of breath, lightheadedness, swelling in the legs
- Gut problems: fever; chills; intense stomach pain or cramps; bloating; skin irritation, swelling, or redness around the anus; discharge from the anus; blood in stool
- Serious liver problems: right-sided stomach pain, tiredness, loss of appetite, yellowing of the skin or eyes
Serious bleeding: unusual bleeding, bleeding that’s hard to stop, easy bruising, blood in urine or stool - Blood clot in the lungs or serious lung problems: cough, chest pain, trouble breathing, shortness of breath, racing heart
- Blood clot near the heart: chest pain, stomach discomfort, sweating, nausea, dizziness
- Blood clot in the leg: leg cramp, swelling, pain, muscle tightness
- Dangerously high blood pressure: anxiety, blurry vision, confusion, chest pain, nausea, vomiting, headache
- Tumor lysis syndrome: fever, chills, nausea or vomiting, confusion, shortness of breath, seizures, irregular heartbeat, dark or cloudy urine, muscle or joint pain, unusual tiredness
Effects of other drugs, drug classes and over-the-counter products on VOTRIENT
The following medications may interact with VOTRIENT:
- Strong CYP3A4 Inhibitors: Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. If coadministration cannot be avoided, reduce the dose of VOTRIENT
- Strong CYP3A4 Inducers: Consider an alternate concomitant medication with no or minimal enzyme induction potential. VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided
- CYP Substrates: Coadministration of VOTRIENT with agents with narrow therapeutic windows that are metabolized by CYP3A4, CYP2D6 or CYP2C8 is not recommended
- Concomitant Use With Simvastatin: Concomitant use of VOTRIENT with simvastatin increases the risk of alanine aminotransferase (ALT) elevations. Increase to weekly monitoring of liver function as recommended Withhold VOTRIENT and resume at reduced dose, or permanently discontinue based on severity of hepatotoxicity
- Concomitant Use With Gastric Acid-Reducing Agents: Avoid concomitant use of VOTRIENT with gastric acid-reducing agents
- Consider short-acting antacids in place of proton pump inhibitors (PPIs) and H2-receptor antagonists. Separate antacid and pazopanib dosing by several hours
Who makes VOTRIENT?
Novartis Pharmaceuticals
Is VOTRIENT safe in pregnancy?
VOTRIENT can harm your unborn baby. Your healthcare provider should check to see if you are pregnant before you start taking VOTRIENT. You should not become pregnant while you are taking VOTRIENT. You should use effective birth control during treatment with VOTRIENT and for at least 2 weeks after your final dose of VOTRIENT. Talk to your healthcare provider about types of birth control that may be
right for you during this time. If you are a male (including one who has had a vasectomy) with a sexual partner who is pregnant, think that they may be pregnant, or who could become pregnant (including those who use other forms of birth control), you should use condoms during sexual intercourse during treatment with VOTRIENT and for at least 2 weeks after the last dose of VOTRIENT.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my VOTRIENT prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your VOTRIENT prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient VOTRIENT savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient VOTRIENT savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for VOTRIENT | Canadian Prescription Savings* for VOTRIENT | VOTRIENT Drug Coupon* | VOTRIENT Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of VOTRIENT?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for VOTRIENT | Canadian Prescription Savings* for VOTRIENT | VOTRIENT Drug Coupon* | VOTRIENT Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the VOTRIENT savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the VOTRIENT drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for VOTRIENT, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the VOTRIENT prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, VOTRIENT is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed VOTRIENT for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the VOTRIENT prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the VOTRIENT prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for VOTRIENT
If you are having trouble paying for your VOTRIENT medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for VOTRIENT you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- VOTRIENT is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers VOTRIENT
- If VOTRIENT is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for VOTRIENT
If you are having trouble paying for your VOTRIENT medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for VOTRIENT you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers VOTRIENT
- If VOTRIENT is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for VOTRIENT
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your VOTRIENT treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for VOTRIENT you will need to meet the following criteria:
- You must be currently insured and have coverage for VOTRIENT
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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NowPatient
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Suite 4200 #1263
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NowPatient is owned and operated by Infohealth Ltd, a licensed online pharmacy with services spanning the UK, US and Rest of the World. Infohealth Ltd is registered in England and Wales under company number 04004930 and our registered office is at Lynwood House, 373 – 375 Station Road, Harrow, England, HA1 2AW.
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NowPatient’s Pharmaceutical services in the UK are provided by Infohealth Limited trading as ‘Infohealth Pharmacy’.
Our dispensing pharmacy is regulated and authorized for internet sales by the General Pharmaceutical Council (GPhC), registration number 1036487. You can view our license credentials on the General Pharmaceutical Council website. Our superintendent pharmacist who is responsible for the safe and effective oversight of medicines supplies is Mr Amish Patel (Registration Number 2042705).
Medicines are not ordinary items of commerce. All medicines or healthcare product sales are made under the supervision of a registered pharmacist who is licensed by the GPhC. At all times, we endeavour to provide a professional and transparent service whose primary goal is to ensure that the best interests of the patient are served.
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Our head of US services is Dr. Jamie Winn.
You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
We do not provide any prescribing services or dispensing services in the United States.
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