Key facts about Vafseo
What is Vafseo?
Vafseo (vadadustat) is an oral tablet used to treat anemia caused by kidney disease.
What dosages is Vafseo available in?
Vafseo is available as a 150 mg, 300 mg and 450 mg oral tablet.
What is Vafseo used for?
Vafseo is a hypoxia-inducible factor prolyl hydroxylase (HIF PH) inhibitor indicated for the treatment of anemia due to chronic kidney disease (CKD) in adults who have been receiving dialysis for at least three months.
How does Vafseo work?
Vafseo works by increasing the production of erythropoietin, which is a hormone responsible for making red blood cells in the body.
How do I take Vafseo?
The recommended starting dose of Vafseo is 300 mg orally once daily, with or without food. The dose can be increased in increments of 150 mg to achieve or maintain hemoglobin levels of 10 g/dL to 11 g/dL. Doses may range from 150 mg to a maximum of 600 mg.
Is it safe for me to take Vafseo?
Vafseo is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you are allergic to vadadustat or any inactive ingredients in the product or if you have uncontrolled blood pressure.
Vafseo Common Side Effects
Common side effects of Vafseo: High blood pressure, diarrhea
Vafseo Serious Side Effects
Serious side effects are rare with Vafseo. Contact your healthcare provider immediately if you experience any of the following: Increased risk of blood clots that may be fatal, including myocardial infarction (MI), stroke, VTE, and vascular access thrombosis. Liver damage, Seizures, Stomach ulcers and bleeding Increased risk of cancer.
Effects of other drugs, drug classes and over-the-counter products on Vafseo
The following medications may interact with Vafseo: Iron supplements and iron-containing phosphate binders: Give Vafseo at least 1 hour before products containing iron. Non-iron-containing phosphate binders: Give Vafseo at least 1 hour before or 2 hours after non-iron-containing phosphate binders. BCRP substrates: Monitor for signs of substrate adverse reactions and consider substrate dose reduction. Statins: Monitor for statin-related adverse reactions.
Who makes Vafseo?
AstraZeneca
Is Vafseo safe in pregnancy?
It is not known if Vafseo may harm your unborn baby. Talk to your healthcare provider if you become pregnant or think you may be pregnant during treatment with Vafseo.
