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Uceris is the brand name for budesonide and is available as an extended-release oral tablet and a rectal foam.

Uceris is available as a 9 mg extended-release oral tablet and a 2 mg per metered dose rectal foam.

Uceris is a corticosteroid and is used to treat mild-to-moderate distal (left-sided) ulcerative colitis (UC).

Uceris is a corticosteroid. It’s applied rectally or taken orally to lower inflammation in the rectum and colon. This can help heal ulcers and ease bloody diarrhea.

Uceris is dosed as follows:

• Each pump of Uceris rectal foam contains 2 mg of budesonide
• Adults: Apply 1 pump into the rectum in the morning and evening (at bedtime) for 2 weeks. Then, apply 1 pump into the rectum once daily at bedtime for 4 more weeks.
• For oral tablets: The recommended dosage for the induction of remission in adult patients with active, mild to moderate ulcerative colitis is one 9 mg tablet to be taken once daily in the morning with or without food for up to 8 weeks

Uceris is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Uceris:

• Rectal foam
• Low blood cortisol levels
• Nausea

Tablets

• Headache
• Nausea
• Decreased blood cortisol
• Upper abdominal pain
• Fatigue
• Gas and bloating
• Acne
• Urinary tract infection
• Joint pain
• Constipation

Serious side effects are rare with Uceris.

The following medications may interact with Uceris:

• Avoid cytochrome P450 3A4 inhibitors (e.g., ketoconazole, grapefruit juice)
• May cause increased systemic corticosteroid effects

Bausch Health

Uceris may harm your unborn baby. Tell your healthcare provider if you are pregnant or think you are pregnant.

• Budesonide