Key facts about Trulance
What is Trulance?
Trulance is the brand name for plecanatide and is available as an oral tablet.
What dosages is Trulance available in?
Trulance is available as a 3 mg oral tablet.
What is Trulance used for?
Trulance is a GC-C agonist and is used for the following:
Irritable bowel syndrome with constipation (IBS-C, repeated stomach pain with a change in bowel movements) Chronic idiopathic constipation (CIC, long-term constipation with an unknown cause)
How does Trulance work?
Trulance is a guanylate cyclase-C (GC-C) agonist. GC-C is a protein that works in the intestines. Trulance activates GC-C, which helps raise the amount of fluid in your intestines and speed up the movement of food through your gut. These actions soften stool, relieve belly pain, and help you have regular bowel movements.
How do I take Trulance?
The typical dose is 3 mg by mouth once a day.
Is it safe for me to take Trulance?
Trulance is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
Patients less than 6 years of age due to the risk of serious dehydration. Patients with known or suspected mechanical gastrointestinal obstruction.
Trulance Common Side Effects
Common side effects of Trulance:
- Diarrhea
Trulance Serious Side Effects
Serious side effects are rare with Trulance. Contact your healthcare provider immediately if you experience any of the following.
- Severe diarrhea
- Bloody stools or black stools that look like tar
- Dehydration: confusion, dizziness, fainting, racing heart
Effects of other drugs, drug classes and over-the-counter products on Trulance
There are no major drug interactions listed for Trulance. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Trulance?
Bausch Health
Is Trulance safe in pregnancy?
It is not known if Trulance will harm your unborn baby. Trulance should be given to a pregnant woman only if clearly needed.
