tofacitinib
Are you tired of high medication costs? Our service offers unbeatable savings on your tofacitinib prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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tofacitinib key facts
What dosages is tofacitinib available in?
tofacitinib is available as a 1 mg/mL oral solution.
What is tofacitinib used for?
tofacitinib is a Janus kinase (JAK) inhibitor that is used to treat:
- Moderate-to-severe rheumatoid arthritis (RA) in adults
Psoriatic arthritis (PsA) in adults - Ankylosing spondylitis (AS) in adults
- Moderate-to-severe ulcerative colitis (UC) in adults
- Moderate-to-severe polyarticular juvenile idiopathic arthritis (pJIA) in children ages 2 years and older – immediate-release tablets and liquid only
How does tofacitinib work?
tofacitinib is a Janus kinase (JAK) inhibitor. It blocks a protein in the body called JAK. This protein plays a role in causing inflammation. By blocking and stopping JAK from working, tofacitinib lowers inflammation in the body.
How do I take tofacitinib?
tofacitinib is dosed as follows:
- Rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis
- IR (immediate-release) tablets: The typical dose is 5 mg by mouth twice daily
- XR (extended-release) tablets: The typical dose is 11 mg by mouth once daily
Ulcerative colitis
- IR tablets: The typical dose is 10 mg by mouth twice daily for at least 8 weeks, then 5 mg by mouth twice daily
- XR tablets: The typical dose is 22 mg by mouth once daily for at least 8 weeks, then 11 mg by mouth once daily
Polyarticular course juvenile idiopathic arthritis
- IR tablets and liquid: The dose is based on your body weight. The typical dose ranges from 3.2 mg to 5 mg by mouth twice daily
Is it safe for me to take tofacitinib?
tofacitinib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
tofacitinib Common Side Effects
Common side effects of tofacitinib:
- Arthritis:
- Upper respiratory tract infection
- Nose and throat infection
- Diarrhea
- Headache
Ulcerative colitis:
- Nose and throat infection
- High cholesterol
- Headache
- Upper respiratory tract infection
- Muscle damage
- Rash
- Diarrhea
- Stomach infection
- Anemia
tofacitinib Serious Side Effects
Serious side effects are rare with tofacitinib. Contact your healthcare provider immediately if you experience any of the following.
- Serious infections: fever, weakness, chills, difficulty breathing, cough, diarrhea, stomach pain, burning when you urinate, urinating more or less often
- Stroke: sudden weakness on one side of your body, trouble speaking, confusion
- Blood clot near or in the heart: chest pain; short of breath; pain in the jaw, neck, or back; feeling weak or lightheaded
- Blood clot in the lung (pulmonary embolism): cough, chest pain, trouble breathing, racing heart
- Blood clot in the leg (deep vein thrombosis): leg cramp, swelling or pain in the leg, muscle tightness
Stomach tear: stomach pain, bloating, change in bowel movements, bleeding - Liver damage: nausea, stomach pain, yellowing of the skin or whites of the eyes
Severe allergic reaction: rash, trouble breathing, feeling faint, swelling of the face or throat - Cancer
Effects of other drugs, drug classes and over-the-counter products on tofacitinib
The following medications may interact with tofacitinib:
- Strong CP3A4 Inhibitors (e.g., ketoconazole): Dosage adjustment of XELJANZ/XELJANZ XR/XELJANZ Oral Solution is recommended
- Moderate CYP3A4 Inhibitors Coadministered with Strong CYP2C19 Inhibitors (e.g., fluconazole): Dosage adjustment of XELJANZ/XELJANZ XR/XELJANZ Oral Solution is recommended
- Strong CYP3A4 Inducers (e.g., rifampin): Coadministration with XELJANZ/XELJANZ XR/XELJANZ Oral Solution is not recommended
- Immunosuppressive Drugs (e.g., azathioprine, tacrolimus, cyclosporine): Risk of added immunosuppression; coadministration with biologic DMARDs or potent immunosuppressants has not been studied in patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, UC, or pcJIA
Who makes tofacitinib?
Various FDA-approved generic manufacturers
Is tofacitinib safe in pregnancy?
XELJANZ/XELJANZ XR/XELJANZ Oral Solution may affect the ability of females to get pregnant. It is not known if this will change after stopping XELJANZ/XELJANZ XR/XELJANZ Oral Solution. It is not known if XELJANZ/XELJANZ XR/XELJANZ Oral Solution will harm an unborn baby. Pregnancy Registry: Pfizer has a registry for pregnant women who take XELJANZ/XELJANZ XR/XELJANZ Oral Solution. The purpose of this registry is to check the health of the pregnant mother and her baby. If you are pregnant or become pregnant while taking XELJANZ/XELJANZ XR/XELJANZ Oral Solution, talk to your healthcare provider about how you can join this pregnancy registry or you may contact the registry at 1-877-311-8972 to enroll.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my tofacitinib prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your tofacitinib prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient tofacitinib savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient tofacitinib savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for tofacitinib | Canadian Prescription Savings* for tofacitinib | tofacitinib Drug Coupon* | tofacitinib Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of tofacitinib?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for tofacitinib | Canadian Prescription Savings* for tofacitinib | tofacitinib Drug Coupon* | tofacitinib Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the tofacitinib savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the tofacitinib drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for tofacitinib, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the tofacitinib prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, tofacitinib is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed tofacitinib for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the tofacitinib prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay contribution, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the tofacitinib prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for tofacitinib
If you are having trouble paying for your tofacitinib medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for tofacitinib you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- tofacitinib is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers tofacitinib
- If tofacitinib is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for tofacitinib
If you are having trouble paying for your tofacitinib medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for tofacitinib you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers tofacitinib
- If tofacitinib is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for tofacitinib
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your tofacitinib treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for tofacitinib you will need to meet the following criteria:
- You must be currently insured and have coverage for tofacitinib
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
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