Key facts about Tobi
What is Tobi?
Tobi is the brand name for tobramycin and is available as an inhalation solution.
What dosages is Tobi available in?
Tobi is available as a 300 mg per 5 mL solution in a single-dose ampule.
What is Tobi used for?
Tobi is an aminoglycoside antibacterial approved for the management of cystic fibrosis in adults and pediatric patients 6 years of age and older with Pseudomonas aeruginosa.
How does Tobi work?
Tobi is an aminoglycoside antibiotic. It kills bacteria by blocking their ability to make proteins that are necessary for their protective covering. By getting rid of the Pseudomonas aeruginosa bacteria in the lungs, Tobi helps people with CF breathe better.
How do I take Tobi?
The typical dose of Tobi is 1 inhalation by mouth every 12 hours. Use this medication for 28 days, then stop for 28 days, then repeat the 28-day cycle.
Is it safe for me to take Tobi?
Tobi is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Known hypersensitivity to any aminoglycoside
Tobi Common Side Effects
Common side effects of Tobi:
- Lung reactions, including cough, shortness of breath, wheezing, “rattling” lung sounds
- Hoarseness
- Mouth or throat pain
- Rash
- Altered taste
Tobi Serious Side Effects
Serious side effects are rare with Tobi. Contact your healthcare provider immediately if you experience any of the following:
- Difficulty breathing or wheezing
- Hearing loss, dizziness, or ringing in the ears
- Muscle weakness
- Kidney injury: less urine, swollen feet or legs
Effects of other drugs, drug classes and over-the-counter products on Tobi
The following medications may interact with Tobi:
- Other drugs with neurotoxic, nephrotoxic, or ototoxic
- Ethacrynic acid
- Furosemide
- Urea
- Intravenous mannitol
Who makes Tobi?
Novartis Pharmaceuticals
Is Tobi safe in pregnancy?
Aminoglycoside antibiotics like Tobi can cause harm to your unborn baby if taken while pregnant. Although Tobi mostly stays in the lungs, if you are pregnant or plan to become pregnant, talk to your provider about the risks and benefits of using this medication.













