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MICARDIS contains telmisartan/hydrochlorothiazide and is available as a 40 mg/12.5 mg, 80 mg/12.5 mg, 80 mg/25 mg oral tablet.

Telmisartan/HCTZ is an ARB/thiazide diuretic that is used to treat high blood pressure.

Telmisartan/HCTZ is a combination of two medications that help lower blood pressure: Telmisartan is an angiotensin II receptor blocker (ARB). It blocks a hormone called angiotensin II that tightens blood vessels and causes your body to hold on to more fluid. Both of these actions can raise your blood pressure. Telmisartan helps to relax your blood vessels, which causes your blood pressure to go down. Hydrochlorothiazide is a thiazide diuretic (water pill) that makes you urinate more. It works in your kidneys to remove extra water and certain electrolytes (like sodium and potassium), which helps lower your blood pressure.

Telmisartan/HCTZ is typically dosed in ranges from 80 mg/12.5 mg (telmisartan/hydrochlorothiazide) to 160 mg/25 mg (telmisartan/hydrochlorothiazide) by mouth once daily.
Your dose might differ if you have liver problems.

Telmisartan/HCTZ is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known hypersensitivity to telmisartan or any component, anuria, or are taking aliskiren.

Common side effects of Telmisartan/HCTZ:

• Cough, sore throat, and other symptoms of an upper respiratory tract infection
• Back pain
• Stuffy nose, sinus pressure, and other symptoms of a sinus infection
• Diarrhea

Serious side effects are rare with Telmisartan/HCTZ. Contact your healthcare provider immediately if you experience any of the following.

• Severe allergic reaction: rash, trouble breathing, swelling of the face, lips, throat
  Severe low blood pressure: dizziness, feeling faint
• Kidney problems: urinating less often than usual, swelling, unexplained weight gain
• Changes in your electrolytes (potassium, sodium, magnesium): nausea, chest pain, irregular heartbeat, thirst, muscle cramps

The following medications may interact with Telmisartan/HCTZ:

• Lithium: Risk of lithium toxicity
• Non-steroidal anti-inflammatory drugs (NSAIDs): Reduced diuretic, natriuretic, and antihypertensive effects; increased risk of renal impairment
• Dual blockade of renin-angiotensin system: Increased risk of renal impairment, hypotension, and hyperkalemia
• Antidiabetic drugs: Dosage adjustment may be required Cholestyramine and colestipol: Reduced absorption of thiazides

Various FDA-approved generic manufacturers

Telmisartan/HCTZ may cause harm to your unborn baby. Discontinue Telmisartan/HCTZ when pregnancy is recognized.

• Micardis HCT