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Tegretol is the brand name for carbamazepine and is available as an oral tablet, chewable tablet, and oral suspension.

Tegretol is available as a 200 mg oral tablet, a 100 mg chewable tablet, and a 100 mg/5 ml oral suspension.

Tegretol is an antiepileptic and is used to treat Partial-onset seizures, generalized tonic-clonic seizures, mixed seizure patterns, and trigeminal neuralgia (facial nerve pain).

Tegretol is an antiepileptic known as a sodium channel blocker. It’s thought to work by blocking the activity of certain nerves in your brain.

Tegretol is typically started at 200 mg by mouth twice per day. The maximum dose is up to 1,000 mg per day for children ages 12-15 years and 1,200 mg per day for people ages 15 years and older, depending on the condition.

Tegretol is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a history of previous bone marrow depression, hypersensitivity to the drug, or known sensitivity to any of the tricyclic compounds, such as amitriptyline, desipramine, imipramine, protriptyline, nortriptyline, have taken an MAOI within the past 14 days or are currently taking nefazodone.

Common side effects of Tegretol include:

• Dizziness
• Sleepiness
• Nausea
• Vomiting
• Difficulty walking or keeping balance
• Constipation
• Itching
• Dry mouth
• Weakness
• Rash
• Blurry vision
• Speech problems

Serious side effects are rare with Tegretol. Contact your healthcare provider immediately if you experience any of the following.

• Suicidal behavior or thoughts of self-harm
• Serious allergic and skin reactions: sore throat, fever, fatigue, rash, hives, painful blisters, skin reddening, skin peeling, swollen lymph nodes
• Low blood cell counts: fever, trouble breathing, chills weakness, unusual bruising or bleeding, and blood in urine, stools, or gums
• Liver problems: severe nausea, vomiting, right-sided stomach pain, fatigue, low or no appetite, yellowing of the skin or eyes
• Low blood sodium levels: nausea, fatigue, headache, confusion, disoriented, hallucinations (seeing things that aren’t real), seizures, unconsciousness

The following medications may interact with Tegretol:

• CYP3A4 inhibitors – Inhibit Tegretol metabolism and can thus increase plasma carbamazepine levels. Drugs that have been shown, or would be expected, to increase plasma carbamazepine levels include aprepitant,cimetidine, ciprofloxacin, danazol, diltiazem, macrolides (e.g., erythromycin, clarithromycin), fluoxetine, fluvoxamine, trazodone, omeprazole, oxybutynin, isoniazid, niacinamide (nicotinamide), azoles (e.g.,ketaconazole, itraconazole, fluconazole, voriconazole), acetazolamide, verapamil, ticlopidine, grapefruit juice, and protease inhibitors
• CYP3A4 inducers – Can increase the rate of Tegretol metabolism. Drugs that may decrease plasma carbamazepine levels include cisplatin, doxorubicin HCl, felbamate, fosphenytoin, rifampin, phenobarbital, phenytoin, primidone, methsuximide, theophylline, aminophylline. See the package insert for the full list of drug interactions

Novartis Pharmaceuticals

Tegretol can cause fetal harm when administered to a pregnant woman. Tell your healthcare
provider right away if you become pregnant while taking Tegretol. Patients should be encouraged to enroll in the NAAED Pregnancy Registry if they become pregnant. This registry is collecting information about the safety of antiepileptic drugs during pregnancy. To enroll, patients
can call the toll-free number 1-888-233-2334 Information on the registry can also be found at the AED pregnancy registry 

• Carbamazepine