Used for Cancer

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Updated on 26 Apr 2024

TECENTRIQ Uses, Side Effects, Interactions, Warnings & Dosing



TECENTRIQ is the brand name for atezolizumab IV injection.

What dosages is TECENTRIQ available in?

What dosages is TECENTRIQ available in?

TECENTRIQ is available as a single-dose vial in strengths of 840 mg/14 mL (60 mg/mL) and 1200 mg/20 mL (60 mg/mL).

What is TECENTRIQ used for?

What is TECENTRIQ used for?

TECENTRIQ is a PD-L1 inhibitor and is used for the following:

  • Non-small cell lung cancer (NSCLC)
  • Early-stage cancer that’s had surgery and chemotherapy, given by itself
  • Cancer that has spread (metastatic), given by itself or with chemotherapy
  • Advanced small cell lung cancer (SCLC), given with chemotherapy
  • Certain liver cancers that can’t be surgically removed or has spread, given with Avastin (bevacizumab)
  • Advanced melanoma in people with a specific mutation, given with other targeted therapy
  • Advanced alveolar soft part sarcoma (ASPS)
How does TECENTRIQ work?

How does TECENTRIQ work?

TECENTRIQ is an immunotherapy medication known as a PD-L1 inhibitor. It blocks the PD-1 pathway, which helps the immune system recognize and attack cancer cells. As a result, the immune system can kill the cancer cells and stop the cancer from growing.

How do I take TECENTRIQ?

How do I take TECENTRIQ?

TECENTRIQ is dosed as follows: This medication is given as an injection into the vein (IV) by a healthcare provider.

  • Adults: For most cancers, there are a few dosing options your healthcare team will decide to use for your TECENTRIQ treatment. Dosing options include 840 mg given every 2 weeks; 1,200 mg given every 3 weeks; or 1,680 mg given every 4 weeks. Which option your provider chooses will depend on your specific cancer diagnosis and whether you’re taking TECENTRIQ with other anticancer medications
  • Children 2 years and older (ASPS only): The dose is based on your child’s body weight. The typical dose is 15 mg/kg given every 3 weeks. Each dose can be up to a maximum of 1,200 mg
Is it safe for me to take TECENTRIQ?

Is it safe for me to take TECENTRIQ?

TECENTRIQ is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

TECENTRIQ Common Side Effects

TECENTRIQ Common Side Effects

Common side effects of TECENTRIQ:

  • Low red blood cells
  • Other abnormal lab test results
  • Low white blood cells
  • Tiredness
  • Higher liver enzyme levels in blood
  • Cough
  • Lower appetite
  • Trouble breathing
  • Muscle pain
  • Nausea
TECENTRIQ Serious Side Effects

TECENTRIQ Serious Side Effects

Serious side effects are rare with TECENTRIQ. Contact your healthcare provider immediately if you experience any of the following.

  • Serious immune-related side effects: rash, diarrhea, trouble breathing, chest pain, severe stomach pain, mucus or blood in stool
  • Serious reaction during infusion: itching, trouble breathing, fast heart beat, feeling warm or hot
Effects of other drugs, drug classes and over-the-counter products on TECENTRIQ

Effects of other drugs, drug classes and over-the-counter products on TECENTRIQ

  • There are no major drug interactions listed for TECENTRIQ. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes TECENTRIQ?

Who makes TECENTRIQ?

Genentech, Inc.

Is TECENTRIQ safe in pregnancy?

Is TECENTRIQ safe in pregnancy?

TECENTRIQ can harm your unborn baby. Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with TECENTRIQ. Females who are able to become pregnant:  Your healthcare provider should do a pregnancy test before you start treatment with TECENTRIQ. You should use an effective method of birth control during your treatment and for at least 5 months after the last dose of  TECENTRIQ.


What to do if you missed your TECENTRIQ dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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