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MEDICAL INFORMATION
Targretin Key Facts
What is Targretin?
Targretin is the brand name for bexarotene and is available as an oral capsule.
What dosages is Targretin available in?
Targretin is available as a 75 mg oral capsule.
What is Targretin used for?
Targretin is a retinoid acid derivative and is used to treat Cutaneous T-cell lymphoma (refractory or persistent).
How does Targretin work?
Targretin is a retinoid acid derivative. It stops cancer cells from growing and multiplying. However, the exact way in which the medication works to treat cutaneous T-cell lymphoma is not known.
How do I take Targretin?
The recommended initial dose of Targretin is 300 mg/m /day. Targretin should
be taken as a single oral daily dose with a meal. Your dose may be adjusted if you experience toxicity or serious side effects.
Is it safe for me to take Targretin?
Targretin is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are pregnant.
Targretin Common Side Effects
Common side effects of Targretin:
- Rash
- Itching
- Pain
Targretin Serious Side Effects
Serious side effects are rare with Targretin.
Effects of other drugs, drug classes and over-the-counter products on Targretin
The following medications may interact with Targretin:
- Gemfibrozil: Concomitant administration of Targretin and gemfibrozil resulted in increases in
- plasma concentrations of bexarotene. Concomitant administration of gemfibrozil with Targretin is
- not recommended.
- Targretin may be an inducer for the CYP3A4 enzymes, and may reduce plasma concentrations of
- other substrates metabolized by CYP3A4. Drug products which may be affected include oral or other
- systemic hormonal contraceptives. Thus, if treatment with Targretin is intended for a female with
- reproductive potential, it is strongly recommended that a non-hormonal contraception be considered.
Who makes Targretin?
Bausch Health
Is Targretin safe in pregnancy?
Targretin is a member of the retinoid class of drugs that is associated with birth defects in humans.
Bexarotene also caused birth defects when administered orally to pregnant rats. Targretin must not
be administered to a pregnant woman.
What is the generic name for Targretin?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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