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Susvimo Injection is the brand name for ranibizumab eye injection.

Susvimo Injection is available as 100 mg/mL solution in a single-dose vial.

Susvimo Injection is a VEGF inhibitor and is used to treat wet age-related macular degeneration (AMD).

Susvimo Injection is a vascular endothelial growth factor (VEGF) inhibitor. VEGF is a protein your body normally makes. But people with wet AMD have high levels of VEGF. Too much VEGF can lead to abnormal blood vessel growth in your eye. These blood vessels can leak into the eye which can lead to vision loss. SUSVIMO works by blocking VEGF directly in your eye so that it slows down abnormal blood vessel growth. This can help protect and possibly improve your vision.

The SUSVIMO implant is placed into your eye during a procedure performed by a healthcare provider. The typical dose is 2 mg continuously released in your eye by the implant with a refill about every 6 months.

Susvimo Injection is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following.

• Ocular or periocular infections
• Active intraocular inflammation
• Hypersensitivity

Common side effects of Susvimo Injection:

• Eye bleeding
• Red eye
• Swelling of the colored part of your eye
• Eye pain
• Eye floaters
• Eye bleb
• Feeling of something being in your eye
• Headache

Serious side effects are rare with Susvimo Injection. Contact your healthcare provider immediately if you experience any of the following.

• Eye infection (endophthalmitis): eye pain, sensitivity to light, loss of vision, eye redness
• Separation of the retina from the back of the eye (retinal detachment): flashing lights, feeling like something is covering your vision, changes in your vision, or vision loss
• Breakdown of the layer that lines your eye (conjunctival erosion): eye discharge, feeling like something is in your eye, watery eyes
• Opening of the layer that lines your eye (conjunctival retraction): eye discharge, feeling like something is in your eye, watery eyes

• There are no major drug interactions listed for Susvimo Injection. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking

Genentech, Inc.

It is not known if SUSVIMO will harm your unborn baby. You should use birth control during your treatment with SUSVIMO and for 12 months after your last dose of SUSVIMO

• Ranibizumab