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MEDICAL INFORMATION
Somatuline Depot Key Facts
What is Somatuline Depot?
Somatuline Depot is the brand name for lanreotide and is available as a subcutaneous injection.
What dosages is Somatuline Depot available in?
Somatuline Depot is available as a 60 mg/0.2 mL, 90 mg/0.3 mL, and 120 mg/0.5 mL single-dose prefilled syringe.
What is Somatuline Depot used for?
Somatuline Depot is used to treat acromegaly, a certain type of tumor in the gut (gastroenteropancreatic neuroendocrine tumors (GEP-NETs)), and symptoms from certain types of tumors (carcinoid syndrome).
How does Somatuline Depot work?
Somatuline Depot is a somatostatin analog. It acts just like somatostatin, a hormone made by your body that blocks the release of many other hormones to treat conditions like acromegaly and certain cancers.
How do I take Somatuline Depot?
Somatuline Depot is typically dosed as follows:
- Acromegaly: The typical starting dose is 90 mg injected under the skin once per month for 3 months by your healthcare provider. After 3 months, your provider might change your dose based on symptoms and lab results.
- GEP-NETs: The typical dose is 120 mg injected under the skin once per month by your healthcare provider.
- Carcinoid syndrome: The typical dose is 120 mg injected under the skin once per month by your healthcare provider. If you’re already being treated for GEP-NETs, you don’t need an additional dose for carcinoid syndrome.
Is it safe for me to take Somatuline Depot?
Somatuline Depot is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Hypersensitivity to lanreotide
Somatuline Depot Common Side Effects
Common side effects of Somatuline Depot:
- Diarrhea
- Gallstones
- Stomach pain
- Injection site reactions
- Joint pain
- Muscle pain
- Vomiting
- Headache
- High blood sugar
- High blood pressure
Somatuline Depot Serious Side Effects
Serious side effects are rare with Somatuline Depot. Contact your healthcare provider immediately if you experience any of the following:
- Dangerously low blood sugar: feeling faint, shaking, sweating, dizziness, fast heartbeat, nervousness, anxious, confused, irritable, feeling very hungry
- Dangerously high blood sugar: frequently thirsty, needing to urinate often, tiredness, nausea, vomiting, difficulty breathing, having fruity breath, having dry mouth
- Low heartbeat: chest pain, dizziness, fatigue, feeling faint
- High blood pressure: severe headaches, nosebleed, fatigue, confusion, chest pain, difficulty breathing
- Swelling of the gallbladder or pancreas: sudden pain in upper right portion of your stomach area, back pain between your shoulder blades, nausea, vomiting, fever, swelling in the belly, fast heartbeat, difficulty breathing
Effects of other drugs, drug classes and over-the-counter products on Somatuline Depot
The following medications may interact with Somatuline Depot:
- Cyclosporine
- Bromocriptine
- Bradycardia-inducing drugs (e.g., beta-blockers)
Who makes Somatuline Depot?
Ipsen Biopharmaceuticals, Inc.
Is Somatuline Depot safe in pregnancy?
It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.
What is the generic name for Somatuline Depot?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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