SEROQUEL XR
Used for Schizophrenia
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Manufactured by AstraZeneca
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SEROQUEL XR Uses, Side Effects, Interactions, Warnings & Dosing
What is SEROQUEL XR?
SEROQUEL XR is the brand name for quetiapine and is available as an extended-release tablet.
What dosages is SEROQUEL XR available in?
SEROQUEL XR is available as a 50 mg, 150 mg, 200 mg, 300 mg, and 400 mg extended-release tablet.
What is SEROQUEL XR used for?
SEROQUEL XR is an atypical antipsychotic and is used to treat the following:
- Schizophrenia in adults and children age 13 years and older
- Bipolar disorder in adults and children age 10 years and older
- Add-on to antidepressants for depression (extended-release only)
How does SEROQUEL XR work?
SEROQUEL XR is an atypical antipsychotic. It’s not completely known how SEROQUEL works, but it’s thought to work by balancing out the levels of chemicals (dopamine and serotonin) in your brain to help control your thoughts, mood, and behaviors.
How do I take SEROQUEL XR?
SEROQUEL XR is dosed as follows:
- Schizophrenia (children and adults): The typical starting dose is 50 mg to 300 mg by mouth once daily, depending on age. Your provider will raise your dose slowly over time. The typical maintenance dose ranges from 400 mg to 800 mg once daily
- Bipolar disorder (children and adults): The typical starting dose is 50 mg to 300 mg by mouth once daily, depending on age and whether or not you’re taking other medications for bipolar disorder. Your provider will raise your dose slowly over time. The typical maintenance dose ranges from 400 mg to 800 mg once daily
- Bipolar depression and depression (adults only): The typical starting dose is 50 mg by mouth once daily. Your provider will raise your dose slowly over time. The typical maintenance dose ranges from 150 mg to 300 mg once daily
Is it safe for me to take SEROQUEL XR?
SEROQUEL XR is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
SEROQUEL XR Common Side Effects
Common side effects of SEROQUEL XR:
- Sleepiness
- Dry mouth
- Dizziness
- Constipation
- Difficulty controlling muscle movements
- Weight gain
SEROQUEL XR Serious Side Effects
Serious side effects are rare with SEROQUEL XR. Contact your healthcare provider immediately if you experience any of the following.
- Seizures
- Suicidal thoughts or actions
- Neuroleptic malignant syndrome: fever, sweating, stiff muscles, confusion, not aware of your surroundings, fast or irregular heartbeat
- Abnormal heart rhythm (QT prolongation): chest pounding, short of breath, chest pain, feeling faint or lightheaded
- Dangerously high blood sugar: frequently thirsty, needing to urinate often, tiredness, nausea, vomiting, difficulty breathing, having fruity breath, having dry mouth
- Serious infections: fever, headache, chills, body aches, cough, weakness
- Severe allergic reactions: swelling of the face, tongue, or throat, difficulty breathing
Effects of other drugs, drug classes and over-the-counter products on SEROQUEL XR
The following medications may interact with SEROQUEL XR:
- P450 3A Inhibitors: May decrease the clearance of quetiapine. Lower doses of quetiapine may be required.
- Hepatic Enzyme Inducers: May increase the clearance of quetiapine
- Higher doses of quetiapine may be required with phenytoin or other inducers
- Centrally Acting Drugs: Caution should be used when quetiapine is used in combination with other CNS acting drugs
- Antihypertensive Agents: Quetiapine may add to the hypotensive effects of these agents
- Levodopa and Dopamine Agents: Quetiapine may antagonize the effect of these drugs
Who makes SEROQUEL XR?
AstraZeneca
Is SEROQUEL XR safe in pregnancy?
SEROQUEL XR use may cause extrapyramidal and/or withdrawal symptoms in neonates with third trimester exposure. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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