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Serevent Diskus is the brand name for salmeterol xinafoate and is available as an inhalation powder.

Serevent Diskus is available as an inhaler containing salmeterol (50 mcg) as a powder formulation for oral inhalation.

Serevent Diskus is a LABA and is used for the following:

• Asthma
• Chronic obstructive pulmonary disease (COPD)
• Prevention of exercise-induced asthma

Serevent Diskus is a long-acting beta-agonist (LABA), which relaxes the airway muscles to make breathing easier.

Serevent Diskus is typically dosed as follows:

• Asthma or COPD: Use 1 inhalation or puff every 12 hours
• Prevention of exercise-induced asthma: Use 1 inhalation at least 30 minutes before you exercise

Serevent Diskus is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

• Asthma: Without concomitant use of an ICS.
• Primary treatment of status asthmaticus or acute episodes of asthma or COPD requiring intensive measures.
• Severe hypersensitivity to milk proteins or demonstrated hypersensitivity to salmeterol or any of the excipients.

Common side effects of Serevent Diskus:

• Headache
• Stuffy nose
• Sore throat
• Flu

Serious side effects are rare with Serevent Diskus. Contact your healthcare provider immediately if you experience any of the following.

• Allergic reaction
• Worsening COPD symptoms
• Paradoxical bronchospasm (breathing and wheezing gets worse)

The following medications may interact with Serevent Diskus:

• Strong cytochrome P450 3A4 inhibitors (e.g., ritonavir, ketoconazole):
• Use not recommended. May increase risk of cardiovascular effects
• Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. May potentiate effect of salmeterol on vascular system.
• Beta-blockers: Use with caution. May block bronchodilatory effects of beta-agonists and produce severe bronchospasm
• Diuretics: Use with caution. Electrocardiographic changes and/or hypokalemia associated with non–potassium-sparing diuretics may worsen with concomitant beta-agonists

GlaxoSmithKline

It is not known if the medicine salmeterol in Serevent Diskus may harm your unborn baby. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

• Salmeterol Xinafoate