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Sabril Sachets is the brand name for vigabatrin and is available as an oral solution.

Sabril Sachets is available as a 500 mg packet for oral solution.

Sabril Sachets is an antiepileptic and is used for the following:

• Difficult-to-treat complex partial seizures in people age 2 years and older (as add-on therapy to other medications)
  Infantile spasms in children age 1 month to 2 years

Sabril Sachets is an antiepileptic (another name for anti-seizure medication). It’s not exactly clear how it works to treat seizures. But it’s thought to raise the levels of gamma-aminobutyric acid (GABA), a chemical in the brain that calms nerves. This helps control seizures.

Sabril Sachets is dosed as follows:

• The dose is the same for the tablet and powder for liquid.

Complex partial seizures

• Age 17 years or older: The typical dose is 500 mg to 1,500 mg by mouth twice per day
• Age 2 to less than 17 years: The dose is based on your child’s body weight
• 22 to 33 pounds: The typical dose is 175 mg to 525 mg by mouth twice per day
• 33 to 44 pounds: The typical dose is 225 mg to 650 mg by mouth twice per day
• 44 to 55 pounds: The typical dose is 250 mg to 750 mg by mouth twice per day
• 55 to 132 pounds: The typical dose is 250 mg to 1,000 mg by mouth twice per day
• Greater than 132 pounds: The typical dose is 500 mg to 1,500 mg by mouth twice per day
• Infantile spasms: The dose is based on your child’s body weight. The starting dose is 25 mg/kg by mouth twice per day. The maximum dose is 75 mg/kg twice per day

Your provider will change the dose depending on how well the medication is working for you and if you’re having side effects. Your dose might differ if you have kidney problems.

Sabril Sachets is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Sabril Sachets:

• Headache
• Dizziness
• Tiredness
• Drowsiness
• Uncontrolled shaking
• Common cold symptoms
• Blurred vision
• Eye twitching
• Diarrhea
• Nausea
• Joint pain
• Abnormal coordination
• Weight gain
• Upper respiratory tract infection

Serious side effects are rare with Sabril Sachets. Contact your healthcare provider immediately if you experience any of the following.

• Permanent vision loss
• Suicidal thoughts or behaviors

The following medications may interact with Sabril Sachets:

• Decreased phenytoin plasma levels: dosage adjustment may be needed

Lundbeck

Sabril Sachets can cause harm to your unborn baby. You and your healthcare provider will have to decide if you should take Sabril Sachets while you are pregnant. Pregnancy Registry: If you become pregnant while taking Sabril Sachets, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry. You can enroll in this registry by calling 1-888-233-2334. Information on the registry can also be found at the website AED pregnancy registry. The purpose of this registry is to collect
information about the safety of antiepileptic medicine during pregnancy.

• Vigabatrin