ritlecitinib
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Manufactured by various FDA-approved generic manufacturers.
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ritlecitinib Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is ritlecitinib available in?
ritlecitinib is available as a 50 mg oral capsule.
What is ritlecitinib used for?
ritlecitinib is a JAK kinase and tyrosine kinase inhibitor and is used to treat severe hair loss (alopecia areata) in people ages 12 years and older.
How does ritlecitinib work?
ritlecitinib is a kinase inhibitor. It works by blocking enzymes (proteins) called Janus kinase (JAK) and tyrosine kinase. This prevents the activation of other proteins in your immune system from attacking hair follicles and causing hair loss.
How do I take ritlecitinib?
ritlecitinib is typically dosed at 50 mg by mouth once daily.
Is it safe for me to take ritlecitinib?
ritlecitinib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
ritlecitinib Common Side Effects
Common side effects of ritlecitinib:
- Headache
- Diarrhea
- Acne
- Rash
- Hives
ritlecitinib Serious Side Effects
Serious side effects are rare with ritlecitinib. Contact your healthcare provider immediately if you experience any of the following.
- Stroke: sudden weakness in your body, trouble speaking, confusion, dizziness
- Arterial thrombosis (blood clot in the heart): chest pain; short of breath; pain in the jaw, neck, or back; feeling weak or light-headed
- Pulmonary embolism (blood clot in the lung): cough, chest pain, trouble breathing, racing heart
Deep vein thrombosis (blood clot in the leg): leg cramp, swelling, pain, muscle tightness - Serious bleeds: bleed or bruise easily, bleeding that’s hard to stop, coughing blood, stomach pain, blood in urine or stool
- Serious infections: fever, difficulty breathing, diarrhea, weakness, cough, stomach pain, sweating, chills, burning when you urinate, urinating more often
Allergic reaction: hives, rash, feeling faint, trouble breathing, swelling of your lips or tongue
Effects of other drugs, drug classes and over-the-counter products on ritlecitinib
The following medications may interact with ritlecitinib:
- Certain CYP3A substrates: Additional monitoring and dose adjustment of CYP3A substrate should be considered.
- Certain CYP1A2 substrates: Additional monitoring and dose adjustment of CYP1A2 substrate should be considered
- Certain CYP3A inducers: Coadministration with strong inducers of CYP3A is not recommended
Who makes ritlecitinib?
Various FDA-approved generic manufacturers
Is ritlecitinib safe in pregnancy?
It is not known if ritlecitinib will harm your unborn baby.
Females who are able to become pregnant: Tell your healthcare provider if you are pregnant or plan to become pregnant during treatment with ritlecitinib. There is a pregnancy registry for people who take ritlecitinib during pregnancy. Report pregnancies to Pfizer Inc. at 1-877-390-2940.
What to do if you missed your ritlecitinib dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Tips
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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