Used for Schizophrenia

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Manufactured by Janssen Pharmaceuticals

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

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RISPERDAL CONSTA Uses, Side Effects, Interactions, Warnings & Dosing



RISPERDAL CONSTA is the brand name for risperidone and is available as a long-acting injection.

What dosages is RISPERDAL CONSTA available in?

What dosages is RISPERDAL CONSTA available in?

RISPERDAL CONSTA is available as 12.5 mg, 25 mg, 37.5 mg, and 50 mg long-acting injection.

What is RISPERDAL CONSTA used for?

What is RISPERDAL CONSTA used for?

  • RISPERDAL CONSTA is an atypical antipsychotic that is used to treat:
  • Schizophrenia in adults
  • Bipolar I disorder in adults


RISPERDAL CONSTA is an atypical antipsychotic. It’s not completely known how RISPERDAL CONSTA works. But it’s thought to work by balancing out the levels of chemicals (dopamine and serotonin) in your brain to help control your thoughts, mood, and behaviors.



  • RISPERDAL CONSTA is taken with oral risperidone (Risperdal) for the first 3 weeks of treatment as you wait for RISPERDAL CONSTA to kick in.
  • The typical dose for RISPERDAL CONSTA is 25 mg injected into the muscle of the upper arm or buttocks every 2 weeks. The maximum dose is 50 mg every 2 weeks.
  • Your dose might differ if you have kidney or liver problems or if you’re taking a medication that interacts with RISPERDAL CONSTA.
Is it safe for me to take RISPERDAL CONSTA?

Is it safe for me to take RISPERDAL CONSTA?

RISPERDAL CONSTA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known hypersensitivity to risperidone, paliperidone, or to any excipients in

RISPERDAL CONSTA Common Side Effects

RISPERDAL CONSTA Common Side Effects

  • Common side effects of RISPERDAL CONSTA:
  • Headache
  • Movement problems (parkinsonism)
  • Dizziness
  • Restlessness
  • Tiredness
  • Dry mouth
  • Constipation
  • Indigestion
  • Sleepiness
  • Pain in arms or legs
  • Weight gain
RISPERDAL CONSTA Serious Side Effects

RISPERDAL CONSTA Serious Side Effects

Serious side effects are rare with RISPERDAL CONSTA. Contact your healthcare provider immediately if you experience any of the following.

Neuroleptic malignant syndrome: fever, sweating, stiff muscles, confusion, not aware of your surroundings, fast or irregular heartbeat
Dangerously high blood sugar: feeling thirsty often, needing to urinate often, tiredness, nausea, vomiting, difficulty breathing, having fruity breath, dry mouth
Serious infections: fever, headache, chills, body aches, cough, weakness
Difficulty swallowing

Effects of other drugs, drug classes and over-the-counter products on RISPERDAL CONSTA

Effects of other drugs, drug classes and over-the-counter products on RISPERDAL CONSTA

  • The following medications may interact with RISPERDAL CONSTA:
  • Due to CNS effects, use caution when administering with other centrallyacting drugs. Avoid alcohol.
  • Due to hypotensive effects, hypotensive effects of other drugs with this
  • potential may be enhanced.
  • Effects of levodopa and dopamine agonists may be antagonized.
  • Cimetidine and ranitidine increase the bioavailability of risperidone.
  • Clozapine may decrease clearance of risperidone.
  • Fluoxetine and paroxetine increase plasma concentrations of risperidone.
  • Carbamazepine and other enzyme inducers decrease plasma concentrations
  • of risperidone.


Janssen Pharmaceuticals

Is RISPERDAL CONSTA safe in pregnancy?

Is RISPERDAL CONSTA safe in pregnancy?

RISPERDAL CONSTA use may cause extrapyramidal and/or withdrawal symptoms in neonates with third trimester exposure. RISPERDAL CONSTA should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. There is a pregnancy exposure registry that monitors pregnancy outcomes in
women exposed to atypical antipsychotics, including RISPERDAL CONSTA,
during pregnancy. Healthcare providers are encouraged to register patients
by contacting the National Pregnancy Registry for Atypical Antipsychotics at
1-866-961-2388 or online at http://womensmentalhealth.org/clinical-andresearch-programs/pregnancyregistry/


What to do if you missed your RISPERDAL CONSTA dose

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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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