ribociclib
Used for Cancer
NowPatient helps you obtain your ribociclib prescription for free or at low-cost. Drug savings programs are suitable for individuals who are insured, don't have insurance or are underinsured and can't afford your medicine.
Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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ribociclib key facts
What dosages is ribociclib available in?
ribociclib is available as a 200 mg oral tablet.
What is ribociclib used for?
ribociclib is a kinase inhibitor and is used to treat HR+/HER2- advanced or metastatic breast cancer.
How does ribociclib work?
ribociclib is a specific type of kinase inhibitor, called a cyclin-dependent kinase 4 and 6 (CDK 4/6) inhibitor. CDK 4/6 are proteins that control cell growth in both normal and cancer cells. These proteins can become overactive in cancer cells and cause the cancer to uncontrollably divide and grow. By blocking CDK 4/6, ribociclib slows the growth of cancer cells.
How do I take ribociclib?
ribociclib is dosed as follows:
If used with other medications (e.g, tamoxifen, fulvestrant, or an aromatase inhibitor): The typical starting dose is 150 mg taken by mouth twice a day.
If used alone (metastatic breast cancer when other treatments haven’t worked): The typical starting dose is 200 mg taken by mouth twice a day.
Your dose might be different if you experience certain side effects, have liver problems, or you’re taking medications that might interact with ribociclib.
If you’re using ribociclib with other medications and you’re a male or a female who hasn’t undergone menopause, your provider might also recommend you take a gonadotropin-releasing hormone (GnRH) agonist.
Is it safe for me to take ribociclib?
ribociclib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
ribociclib Common Side Effects
Common side effects of ribociclib:
- Low white blood cell counts
- Nausea
- Infection
- Tiredness
- Diarrhea
- Joint pain
- Hair loss
- Vomiting
- Constipation
- Rash
- Cough
- Headache
- Itchy skin
- Back pain
ribociclib Serious Side Effects
Serious side effects are rare with ribociclib. Contact your healthcare provider immediately if you experience any of the following.
Lung problems: cough, trouble breathing, shortness of breath, chest pain
Effects of other drugs, drug classes and over-the-counter products on ribociclib
The following medications may interact with ribociclib:
- CYP3A4 Inhibitors: Avoid concomitant use of ribociclib with strong
- CYP3A inhibitors. If strong inhibitors cannot be avoided, reduce ribociclib
- dose.
- CYP3A4 Inducers: Avoid concomitant use of ribociclib with strong
- CYP3A inducers.
- CYP3A Substrates: The dose of sensitive CYP3A substrates with narrow
- therapeutic indices may need to be reduced when given concurrently with
- ribociclib.
- Drugs Known to Prolong QT Interval: Avoid concomitant use of drugs
- known to prolong QT interval, such as anti-arrhythmic medicines.
Who makes ribociclib?
Various FDA-approved generic manufacturers
Is ribociclib safe in pregnancy?
Based on findings from animal studies and the mechanism of action, ribociclib can cause fetal harm when administered to a pregnant woman. If you can become pregnant, you should use effective contraception during therapy with ribociclib and for at least 3 weeks after the last dose.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my ribociclib prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your ribociclib prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient ribociclib savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient ribociclib savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for ribociclib | Canadian Prescription Savings* for ribociclib | ribociclib Drug Coupon* | ribociclib Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of ribociclib?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for ribociclib | Canadian Prescription Savings* for ribociclib | ribociclib Drug Coupon* | ribociclib Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the ribociclib savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the ribociclib drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for ribociclib, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the ribociclib prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, ribociclib is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed ribociclib for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the ribociclib prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay contribution, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the ribociclib prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for ribociclib
If you are having trouble paying for your ribociclib medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for ribociclib you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- ribociclib is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers ribociclib
- If ribociclib is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for ribociclib
If you are having trouble paying for your ribociclib medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for ribociclib you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers ribociclib
- If ribociclib is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for ribociclib
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your ribociclib treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for ribociclib you will need to meet the following criteria:
- You must be currently insured and have coverage for ribociclib
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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