PREVYMIS
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Manufactured by Merck & Co., Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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PREVYMIS Uses, Side Effects, Interactions, Warnings & Dosing
What is PREVYMIS?
PREVYMIS is the brand name for letermovir and is available as an oral tablet and IV injection.
What dosages is PREVYMIS available in?
PREVYMIS is available as a 240 mg and 480 mg oral tablet and a 240 mg/12 mL (20 mg/mL) or 480 mg/24 mL (20 mg/mL) IV injection.
What is PREVYMIS used for?
PREVYMIS is an antiviral and is used to prevent cytomegalovirus (CMV) infection in adults:
Who received a stem cell transplant and tests positive for CMV
Who received a kidney transplant and are at high risk for CMV infection
How does PREVYMIS work?
PREVYMIS is an antiviral medication. It stops a certain enzyme (protein) in cytomegalovirus (CMV) from working. This prevents the virus from being able to replicate (copy itself) and grow.
How do I take PREVYMIS?
PREVYMIS is typically started right before or within a month after you’ve received your stem cell or kidney transplant. You’ll continue to take this medication until 100 days after your stem cell transplant, or 200 days after your kidney transplant.
The typical dose is 480 mg by mouth once daily. If you can’t take medications by mouth, PREVYMIS can also be given as an injection into the veins (IV) by a healthcare provider.
Your dose might differ if you’re also taking cyclosporine.
Is it safe for me to take PREVYMIS?
PREVYMIS is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. PREVYMIS is contraindicated with:
Pimozide.
Ergot Alkaloids.
Pitavastatin and simvastatin when co-administered with cyclosporine.
PREVYMIS Common Side Effects
Common side effects of PREVYMIS:
- Nausea
- Diarrhea
- Vomiting
- Swelling in arms or legs
- Cough
- Headache
- Fatigue
- Stomach pain
PREVYMIS Serious Side Effects
Serious side effects are rare with PREVYMIS.
Effects of other drugs, drug classes and over-the-counter products on PREVYMIS
The following medications may interact with PREVYMIS:
- Dosage Adjustment: If PREVYMIS is co-administered with
- cyclosporine, the dosage of PREVYMIS should be decreased to
- 240 mg once daily.
- Co-administration of PREVYMIS may alter the plasma concentrations
- of other drugs and other drugs may alter the plasma concentrations
- of PREVYMIS. Consult the full prescribing information prior to and
- during treatment for potential drug interactions.
Who makes PREVYMIS?
Merck & Co., Inc.
Is PREVYMIS safe in pregnancy?
No adequate human data are available to establish whether PREVYMIS poses a risk to pregnancy
outcomes. PREVYMIS should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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