Key facts about Pentosan Polysulfate Sodium
What dosages is Pentosan Polysulfate Sodium available in?
Pentosan Polysulfate Sodium is available as a 100 mg oral capsule.
What is Pentosan Polysulfate Sodium used for?
- Pentosan Polysulfate Sodium is an urinary analgesic and is used to relieve bladder pain and discomfort caused by bladder pain syndrome (interstitial cystitis)
How does Pentosan Polysulfate Sodium work?
Pentosan Polysulfate Sodium is an urinary analgesic. It’s not fully clear how Pentosan Polysulfate Sodium works. It’s believed that it sticks to the wall of the bladder and acts as a barrier in order to protect your bladder from irritating substances in your urine.
How do I take Pentosan Polysulfate Sodium?
- Pentosan Polysulfate Sodium is typically dosed at 100 mg by mouth 3 times per day with water, at least 1 hour before or 2 hours after meals
Is it safe for me to take Pentosan Polysulfate Sodium?
Pentosan Polysulfate Sodium is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Pentosan Polysulfate Sodium Common Side Effects
Common side effects of Pentosan Polysulfate Sodium:
- Bleeding from the rectum
- Bleeding from the retina of the eye
- Hair loss
- Diarrhea
- Nausea
- Headache
- Rash
- Stomach pain
- Upset stomach
- Abnormal liver tests
- Dizziness
Pentosan Polysulfate Sodium Serious Side Effects
Serious side effects are rare with Pentosan Polysulfate Sodium.
Effects of other drugs, drug classes and over-the-counter products on Pentosan Polysulfate Sodium
- There are no major drug interactions listed for Pentosan Polysulfate Sodium. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes Pentosan Polysulfate Sodium?
Various FDA-approved generic manufacturers
Is Pentosan Polysulfate Sodium safe in pregnancy?
Adequate and well-controlled studies have not been performed in pregnant women using Pentosan Polysulfate Sodium. Because animal studies are not always predictive of human response, this drug should be used in pregnancy only if clearly needed.













