OPUVIZ
Used for Blindness
NowPatient helps you obtain your OPUVIZ prescription for free or at low-cost. Drug savings programs are suitable for individuals who are insured, don't have insurance or are underinsured and can't afford your medicine.
Manufactured by Samsung Bioepis Co., Ltd.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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OPUVIZ key facts
What is OPUVIZ?
Opuviz (aflibercept-yszy) is an injection given in the eye to reduce swelling and prevent vision loss in certain conditions. It is biosimilar to Eyelea.
What dosages is OPUVIZ available in?
Opuviz is available as a 2 mg (0.05 mL of 40 mg/mL) solution in a single-dose vial.
What is OPUVIZ used for?
Opuviz is a vascular endothelial growth factor (VEGF) inhibitor indicated for the treatment of patients with: Neovascular (Wet) Age-Related Macular Degeneration (AMD) Macular Edema Following Retinal Vein Occlusion (RVO) Diabetic Macular Edema (DME) Diabetic Retinopathy (DR)
How does OPUVIZ work?
Opuviz is an anti-vascular endothelial growth factor (anti-VEGF). It works by blocking VEGF, a protein that causes abnormal blood vessels to grow in the eye and leak fluid. This fluid leakage can damage the retina and affect vision, potentially leading to vision loss. By blocking VEGF, it can help prevent vision loss in certain conditions.
How do I take OPUVIZ?
Opuviz is given as a 2 mg (0.05 mL of 40 mg/mL solution) injection in your eye every 4 weeks. Your dose may be then given every 8 weeks after a certain number of doses depending on the condition being treated.
Is it safe for me to take OPUVIZ?
Opuviz is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you have any of the following conditions or if any of the following apply to you: Allergy to aflibercept or any of the inactive ingredients in the product Infection in or around your eye Active eye inflammation
OPUVIZ Common Side Effects
Common side effects of Opuviz: Blood spots on the whites of your eyes, Cataract Eye pain, Increased eye pressure, Eye floaters
OPUVIZ Serious Side Effects
Serious side effects are rare with Opuviz. Contact your healthcare provider immediately if you experience any of the following: Eye infections: red eyes, light sensitivity, eye pain, changes in vision Severely increased eye pressure: intense eye pain, blurred vision, nausea Stroke: sudden confusion, severe headache, facial drooping, slurred speech, weakness on one side of your body Heart attack: chest pain that travels to your jaw or arm, shortness of breath, sweating
Effects of other drugs, drug classes and over-the-counter products on OPUVIZ
There are no drug interactions listed for Opuviz.
Who makes OPUVIZ?
Samsung Bioepis Co., Ltd.
Is OPUVIZ safe in pregnancy?
It is not know whether Opuviz will harm your unborn baby. It did cause birth defects in animal studies. Therefore, Opuviz should only be used if the benefits outweigh the risks.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my OPUVIZ prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your OPUVIZ prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient OPUVIZ savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient OPUVIZ savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for OPUVIZ | Canadian Prescription Savings* for OPUVIZ | OPUVIZ Drug Coupon* | OPUVIZ Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of OPUVIZ?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for OPUVIZ | Canadian Prescription Savings* for OPUVIZ | OPUVIZ Drug Coupon* | OPUVIZ Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the OPUVIZ savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the OPUVIZ drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for OPUVIZ, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the OPUVIZ prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, OPUVIZ is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed OPUVIZ for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the OPUVIZ prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the OPUVIZ prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for OPUVIZ
If you are having trouble paying for your OPUVIZ medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for OPUVIZ you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- OPUVIZ is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers OPUVIZ
- If OPUVIZ is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for OPUVIZ
If you are having trouble paying for your OPUVIZ medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for OPUVIZ you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers OPUVIZ
- If OPUVIZ is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for OPUVIZ
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your OPUVIZ treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for OPUVIZ you will need to meet the following criteria:
- You must be currently insured and have coverage for OPUVIZ
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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