OPSYNVI
Used for Hypertension
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Manufactured by Actelion Pharmaceuticals US, Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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OPSYNVI Uses, Side Effects, Interactions, Warnings & Dosing
What is OPSYNVI?
Opsynvi (macitentan and tadalafil) is an oral tablet used to treat pulmonary arterial hypertension (PAH).
What dosages is OPSYNVI available in?
Opsynvi is available as film-coated tablets containing: macitentan 10 mg and tadalafil 20 mg macitentan 10 mg and tadalafil 40 mg
What is OPSYNVI used for?
Opsynvi is a combination of macitentan, an endothelin receptor antagonist (ERA), and tadalafil, a phosphodiesterase 5 (PDE5) inhibitor, indicated for chronic treatment of pulmonary arterial hypertension (PAH).
How does OPSYNVI work?
By blocking endothelin and PDE5, Opsynvi relaxes the blood vessels that go from your heart to your lungs. This allows more blood to flow through, which lowers the amount of work your heart needs to do to pump blood to your lungs to get oxygen for your body.
How do I take OPSYNVI?
Opsynvi is given as 1 tablet once daily with or without food.
Is it safe for me to take OPSYNVI?
Opsynvi is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you are allergic to any ingredients in Opsynvi, are pregnant, or are taking organic nitrates or guanylate cyclase (GC) stimulators.
OPSYNVI Common Side Effects
Common side effects of Opsynvi: Fluid build up or swelling Anemia Headache Nausea Vomiting Stomach pain Muscle or back pain Pain in arm or leg Low blood pressure Common cold symptoms Flushing
OPSYNVI Serious Side Effects
Serious side effects are rare with Opsynvi. Contact your healthcare provider immediately if you experience any of the following: Liver problems: swelling of the stomach, yellowing of the skin or the whites of the eyes, dark or brown urine, confusion Low blood pressure: dizziness, light headedness, nausea, blurred vision, shallow and fast breathing, tiredness, fainting Anemia (low red blood cell count): tiredness, shortness of breath, irregular heartbeat, dizziness, chest pain, pale skin Fluid build up in the body: shortness of breath; swelling in the legs, ankles, or feet; irregular heartbeat; chest pain; unable to exercise; tiredness; unusual weight gain Hearing or vision loss
Effects of other drugs, drug classes and over-the-counter products on OPSYNVI
The following medications may interact with Opsynvi: Strong CYP3A4 inducers/inhibitors: Avoid concomitant use. Moderate dual or combined CYP3A4 and CYP2C9 inhibitors: Avoid concomitant use.
Who makes OPSYNVI?
Actelion Pharmaceuticals US, Inc.
Is OPSYNVI safe in pregnancy?
Opsynvi can cause serious birth defects if taken during pregnancy. Females must not be pregnant when they start taking Opsynvi or become pregnant during treatment or for 1 month after stopping treatment with Opsynvi.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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