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Opdivo is the brand name for nivolumab and is available as an IV infusion.

Opdivo is available as a 40 mg/4 mL (10 mg/mL), 100 mg/10 mL (10 mg/mL), 120 mg/12 mL (10 mg/mL), and 240 mg/24 mL (10 mg/mL) solution in a single-dose vial.

Opdivo O is a programmed death receptor-1 (PD-1)-blocking antibody indicated for the treatment of certain types of cancer.

Opdivo works by helping your immune system slow or stop the spread of cancer cells. It is a monoclonal antibody.

Opdivo is only available as an intravenous (IV) infusion through your vein that’s administered by a healthcare provider. The dose depends on your body weight and what type of cancer being treated.

Opdivo is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Opdivo when used alone:

• Fatigue
• Rash
• Musculoskeletal pain
• Rash
• Diarrhea
• Nausea
• Weakness
• Cough
• Shortness of breath
• Constipation
• Decreased appetite
• Back pain
• Joint pain
• Upper respiratory tract infection
• Fever
• Headache
• Abdominal pain
• Vomiting
• Urinary tract infection

Serious side effects are rare with Opdivo. Contact your doctor if you experience any of the following.

• Severe infusion reactions
• Complications of stem cell transplant that uses donor stem cells (allogeneic)

There are no major drug interactions listed for Opdivo. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Bristol-Myers Squibb

Opdivo can harm your unborn baby. Females who are able to become pregnant: Your healthcare provider should do a pregnancy test before you start receiving Opdivo. You should use an effective method of birth control during treatment and for 5 months after your last dose of Opdivo. Talk to your healthcare provider about birth control methods that you can use during this time. Tell your healthcare provider right away if you become pregnant during treatment with Opdivo.

• Nivolumab