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Nulojix is the brand name for belatacept and is available as an IV infusion.

Nulojix is available as 250 mg per vial.

Nulojix is an immunosuppressant that is used for the prevention of kidney transplant rejection in adults.

Nulojix s a type of immunosuppressant called a selective T-cell costimulation blocker. It attaches to two spots on the surface of immune cells in your body. These immune cells normally activate (wake up) T-cells. By binding to these spots, it can stop T-cells from multiplying and causing rejection of your transplanted organ.

Nulojix is only available as an intravenous (IV) infusion through your vein that’s administered by a healthcare provider. The dose depends on your body weight and how much time has passed since your transplant. In general, you’ll follow a dosing schedule your transplant provider sets for you, and then eventually, you’ll only receive one dose per month.

Nulojix is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are EBV seronegative or with unknown EBV serostatus.

Common side effects of Nulojix:

• Anemia
• Changes in stool habits
• Urinary tract infection
• Swelling in your arms and legs
• Changes in blood pressure
• Fever
• Cough
• Vomiting
• Headache

Serious side effects are rare with Nulojix. Contact your healthcare provider immediately if you experience any of the following.

• Post-transplant lymphoproliferative disorder (PTLD): changes in mood or usual behavior, confusion, weakness, problems thinking, memory loss, changes in walking or talking, changes in vision
• Infection: fever, chills, muscle aches, change in appetite, weight loss, vomiting, skin rash

The following medications may interact with Nulojix:

• Monitor for a need to adjust concomitant mycophenolate mofetil (MMF) dosage whenna patient’s therapy is switched between cyclosporine and Nulojix
• Coadministration (at the same or nearly the same time) of anti-thymocyte globulin(or any other cell-depleting induction treatment) and Nulojix in kidney transplant recipients, especially those with other predisposing risk factors for venous thrombosis of the renal allograft, may pose a risk for venous thrombosis of the renal
• allograft

Bristol-Myers Squibb

It is not known if Nulojix will harm your unborn baby. If you become pregnant while taking Nulojix: Tell your doctor right away.  You and your doctor should decide if you will keep receiving Nulojix while you are pregnant. Talk with your doctor about enrolling in the National Transplant Pregnancy Registry (NTPR). This Registry collects information about pregnancies in women who have received Nulojix or if their partner has received Nulojix, and had a transplant. You can also enroll by calling 1-877-955-6877.

• Belatacept