NIVESTYM
Are you tired of high medication costs? Our service offers unbeatable savings on your NIVESTYM prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by Pfizer
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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NIVESTYM key facts
What is NIVESTYM?
NIVESTYM is the brand name for filgrastim-aafi and is available as an injection for subcutaneous or IV use.
What dosages is NIVESTYM available in?
NIVESTYM is available as one of the following:
- 300 mcg/mL in a single-dose vial
- 480 mcg/1.6 mL (300 mcg/mL) in a single-dose vial
- 300 mcg/0.5 mL in a single-dose prefilled syringe
- 480 mcg/0.8 mL in a single-dose prefilled syringe
What is NIVESTYM used for?
NIVESTYM is a colony-stimulating factor and is used for the following:
Prevention of low neutrophil-related complications in:
- People getting bone marrow-suppressing chemotherapy
- People with acute myeloid leukemia (AML) after induction or consolidation chemotherapy
- People with cancer who received bone marrow transplants
- People with severe, long-term neutropenia (low neutrophils)
- Preparation for blood collection for your own stem cell transplant (Neupogen, Nivestym, and Zarxio only)
- Increase survival in people exposed to bone marrow-suppressing radiation (Neupogen only)
How does NIVESTYM work?
NIVESTYM is a granulocyte colony-stimulating factor (G-CSF). It works like the G-CSF protein that you naturally have in your body. G-CSF stimulates (triggers) your bone marrow to make neutrophils, a type of white blood cell that helps your body fight infections.
How do I take NIVESTYM?
Your dose depends on your weight, your blood cell counts, and the condition you’re taking the medication for. In general, the typical starting dose is 5 mcg/kg to 10 mcg/kg of body weight per day. It’s given once or twice per day, depending on why you’re taking it. NIVESTYM is given as an injection under the skin (subcutaneously) or an injection through the veins (intravenously, IV).
Is it safe for me to take NIVESTYM?
NIVESTYM is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a history of serious allergic reactions to human granulocyte colony-stimulating factors such as filgrastim products or pegfilgrastim products.
NIVESTYM Common Side Effects
Common side effects of NIVESTYM:
- Fever
- Nausea
- Low platelets
- Feeling weak or tired
- Dizziness
- Cough
- Rash
- Shortness of breath
- Chest pain
NIVESTYM Serious Side Effects
Serious side effects are rare with NIVESTYM. Contact your healthcare provider immediately if you experience any of the following.
- Shortness of breath or trouble breathing
- Ruptured spleen: pain in your left upper stomach or shoulder
- Kidney damage: swelling of face or ankles, dark colored urine, blood in urine, urinating less
- Low platelet count: easy bruising, longer bleeding time, blood in urine or stools
- Serious allergic reaction: rash, face swelling, shortness of breath, fast heart rate
Effects of other drugs, drug classes and over-the-counter products on NIVESTYM
There are no major drug interactions listed for NIVESTYM. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes NIVESTYM?
Pfizer
Is NIVESTYM safe in pregnancy?
It is not known if NIVESTYM harms your unborn baby. NIVESTYM should be given to a pregnant woman only if clearly needed. Talk to your doctor about stopping INFLECTRA if you
are pregnant or planning to become pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my NIVESTYM prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your NIVESTYM prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient NIVESTYM savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient NIVESTYM savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for NIVESTYM | Canadian Prescription Savings* for NIVESTYM | NIVESTYM Drug Coupon* | NIVESTYM Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of NIVESTYM?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for NIVESTYM | Canadian Prescription Savings* for NIVESTYM | NIVESTYM Drug Coupon* | NIVESTYM Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the NIVESTYM savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the NIVESTYM drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for NIVESTYM, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the NIVESTYM prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, NIVESTYM is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed NIVESTYM for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the NIVESTYM prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the NIVESTYM prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for NIVESTYM
If you are having trouble paying for your NIVESTYM medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for NIVESTYM you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- NIVESTYM is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers NIVESTYM
- If NIVESTYM is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for NIVESTYM
If you are having trouble paying for your NIVESTYM medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for NIVESTYM you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers NIVESTYM
- If NIVESTYM is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for NIVESTYM
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your NIVESTYM treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for NIVESTYM you will need to meet the following criteria:
- You must be currently insured and have coverage for NIVESTYM
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
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