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Nemolizumab-Ilto is available as a single-dose, prefilled, dual-chamber pen containing 30 mg of Nemolizumab-Ilto lyophilized powder and diluent, water for injection.

Nemolizumab-Ilto is a monoclonal antibody used to treat prurigo nodularis and atopic dermatitis.

Nemolizumab-Ilto is an interleukin-31 receptor antagonist. IL-31 is a protein that triggers intense itching and skin inflammation, among other effects. By blocking IL-31, Nemolizumab-Ilto helps reduce the urge to scratch. This can, in turn, prevent the development of new nodules (bumps).

Nemolizumab-Ilto is typically dosed as follows:

• Prurigo Nodularis
• Adult Patients Weighing Less Than 90kg: An initial dose of 60 mg (two 30 mg injections), followed by 30 mg
• Given every 4 weeks.
• Adult Patients Weighing 90kg or More: An initial dose of 60 mg (two 30 mg injections), followed by 60 mg
• Given every 4 weeks.
• Atopic Dermatitis
• An initial dose of 60 mg (two 30
• Mg injections), followed by 30 mg given every 4 weeks.

Nemolizumab-Ilto is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

• Known hypersensitivity to Nemolizumab-Ilto or to any of the excipients in the product

Common side effects of Nemolizumab-Ilto:

• Headache
• Joint pain
• Muscle pain
• Skin rashes

Serious side effects are rare with Nemolizumab-Ilto. Contact your healthcare provider immediately if you experience any of the following:

• Allergic reaction

There are no major drug interactions listed for this medication. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Various FDA-approved generic manufacturers

It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.

• Nemluvio