Key facts about Motegrity
What is Motegrity?
Motegrity is the brand name for prucalopride and is available as an oral tablet.
What dosages is Motegrity available in?
Motegrity is available as a 1 mg and 2 mg oral tablet.
What is Motegrity used for?
Motegrity is a serotonin receptor agonist and is used to treat long-term constipation due to an unclear cause (idiopathic) in adults.
How does Motegrity work?
Motegrity is a serotonin receptor agonist. It targets the serotonin receptors (or proteins) in your colon that trigger natural contractions of your colon muscles (known as peristalsis). This helps push food through your digestive tract so that stool can pass more loosely and easily.
How do I take Motegrity?
Motegrity is typically dosed as 2 mg by mouth once daily. If you have severe kidney problems, your dose may be adjusted to 1 mg by mouth once daily.
Is it safe for me to take Motegrity?
Motegrity is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Hypersensitivity to Motegrity
- Intestinal perforation or obstruction due to structural or functional disorder of the gut wall, obstructive ileus, severe inflammatory conditions of the intestinal tract such as Crohn’s disease, ulcerative colitis, and toxic megacolon/megarectum
Motegrity Common Side Effects
Common side effects of Motegrity:
- Headache
- Abdominal pain
- Nausea
- Diarrhea
Motegrity Serious Side Effects
Serious side effects are rare with Motegrity. Contact your healthcare provider immediately if you experience any of the following.
- Suicidal thoughts and behavior
Effects of other drugs, drug classes and over-the-counter products on Motegrity
There are no major drug interactions listed for Motegrity. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Motegrity?
Shire US Inc.
Is Motegrity safe in pregnancy?
It is not known if Motegrity will harm your unborn baby. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
