mirikizumab-mrkz
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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mirikizumab-mrkz Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is mirikizumab-mrkz available in?
mirikizumab-mrkz is available in the following:
- Intravenous Infusion
- Injection: 300 mg/15 mL (20 mg/mL) solution in a single-dose vial
- Subcutaneous Injection
- Injection: 100 mg/mL solution in a single-dose prefilled pen
What is mirikizumab-mrkz used for?
mirikizumab-mrkz is an interleukin-23 antagonist and is used to treat moderate-to-severe active ulcerative colitis in adults.
How does mirikizumab-mrkz work?
mirikizumab-mrkz is a condition that happens when your own immune system attacks your gut. This causes inflammation in the lining of the colon. In particular, proteins called interleukin-23 (IL-23) play a key role in causing gut inflammation in ulcerative colitis. This inflammation can lead to symptoms like stomach pain and cramping, bloody stools, and diarrhea. mirikizumab-mrkz is a type of medication called an interleukin-23 antagonist. It blocks IL-23 from working. And when IL-23 can’t work like usual, it helps reduce inflammation. This helps lessen symptoms of ulcerative colitis.
How do I take mirikizumab-mrkz?
Treatment with mirikizumab-mrkz has two phases: induction and maintenance.
- Induction phase (until month 2 of treatment): The typical induction dose is 300 mg given as an intravenous (IV) infusion every month for the first 3 doses. These infusions are administered by a healthcare professional at a medical center
- Maintenance phase (month 3 and onwards): The typical maintenance dose is 200 mg (two 100 mg prefilled pens) injected under the skin every month
Is it safe for me to take mirikizumab-mrkz?
mirikizumab-mrkz is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
mirikizumab-mrkz Common Side Effects
Common side effects of mirikizumab-mrkz:
- Upper respiratory tract infections
- Injection site reaction
- Joint pain
mirikizumab-mrkz Serious Side Effects
Serious side effects are rare with mirikizumab-mrkz. Contact your healthcare provider immediately if you experience any of the following.
- Allergic reaction: swelling of face or throat, trouble breathing, hives, itching
- Severe infection: fever, chills, sweating, weakness, flu-like symptoms, muscle pain or weakness, unexplained weight loss
- Liver injury: unexplained rash, yellowing of skin or eyes, vomiting, abdominal pain
Effects of other drugs, drug classes and over-the-counter products on mirikizumab-mrkz
There are no major drug interactions listed for mirikizumab-mrkz. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes mirikizumab-mrkz?
Various FDA-approved generic manufacturers
Is mirikizumab-mrkz safe in pregnancy?
It is not known if mirikizumab-mrkz can harm an unborn baby. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. There will be a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to mirikizumab-mrkz during pregnancy. Pregnant women exposed to mirikizumab-mrkz and healthcare providers are encouraged to call Eli Lilly and Company at 1-800-Lilly-Rx (1-800-545-5979).
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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