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Mesalamine DR is available as a 400 mg delayed-release oral capsule.

Mesalamine DR is an aminosalicylate and is used to treat ulcerative colitis (UC).

Mesalamine DR is an aminosalicylate. It’s unclear how mesalamine exactly works. But it appears to work inside the bowels (gut) to lower gut inflammation, which helps relieve symptoms of UC.

Mesalamine DR is dosed as follows:

• Adults: The typical dose is 800 mg (two 400 mg capsules) by mouth three times a day. You’ll typically take the medication for 6 weeks
• Children 5 years or older weighing 37 lbs to 198 lbs: The provider will determine the dose based on your child’s body weight. The medication is taken by mouth twice a day for 6 weeks. The maximum daily dosage ranges from 1.2 to 2.4 grams per day

Mesalamine DR is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known or suspected hypersensitivity to salicylates or aminosalicylates or to any of the ingredients of DELZICOL capsules.

Common side effects of Mesalamine DR:

• Headache
• Stomach pain
• Nausea
• Diarrhea
• Indigestion

Serious side effects are rare with Mesalamine DR. Contact your healthcare provider immediately if you experience any of the following.

• Worsening UC symptoms
• Kidney problems (including kidney stones): trouble urinating, change in how much you urinate, blood in the urine, back or side pain, fever, chills
  Liver problems: yellowing of the skin or eyes, dark urine, stomach pain, tiredness
• Allergic reaction: rash; hives; itchy skin; difficulty breathing; swelling of face, mouth, tongue, or throat
• Severe skin reaction: hives, discolored patches of skin, peeling skin, blisters; with or without fever or body aches

There are no major drug interactions listed for Mesalamine DR. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Various FDA-approved generic manufacturers

There are no adequate and well controlled studies of DELZICOL use in pregnant women. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

• Delizicol