Key facts about Mannitol
What dosages is Mannitol available in?
Mannitol is available as 40 mg of Mannitol per capsule.
What is Mannitol used for?
Mannitol is a prescription inhalation powder medication used as an add-on maintenance therapy to improve lung function in adults (18 years and older) with cystic fibrosis (CF).
How does Mannitol work?
Mannitol contains Mannitol, a sugar alcohol that acts as an osmotic agent. When inhaled as a dry powder, it is thought to draw water into the airways, which helps to thin the thick, sticky mucus characteristic of CF, making it easier to cough out.
How do I take Mannitol?
For the treatment of cystic fibrosis:
- 400 mg of Mannitol (10 capsules)
- Twice a day by oral inhalation, in the morning and evening, with the later
- Dose taken 2-3 hours before bedtime.
Is it safe for me to take Mannitol?
Mannitol is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Hypersensitivity to Mannitol or to any of the capsule components
- Failure to pass the Mannitol Tolerance Test
Mannitol Common Side Effects
Common side effects of Mannitol:
- Cough or coughing up blood
- Mouth or throat pain
- Vomiting
- Fever
- Joint pain
Mannitol Serious Side Effects
Serious side effects are rare with Mannitol. Contact your healthcare provider immediately if you experience any of the following:
- Severe brochospasm and trouble breathing
- Allergic reaction
Effects of other drugs, drug classes and over-the-counter products on Mannitol
There are no major drug interactions listed for this medication. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Mannitol?
Various FDA-approved generic manufacturers
Is Mannitol safe in pregnancy?
It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.













