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Lebrikizumab-Lbkz is available as a 250 mg/2 mL single-dose prefilled pen or single-dose prefilled syringe.

Lebrikizumab-Lbkz is an injectable medication that’s used to treat moderate-to-severe eczema.

Lebrikizumab-Lbkz is a type of monoclonal antibody called an interleukin-13 (IL-13) antagonist. It blocks a protein in your body called IL-13, which plays a role in causing eczema. By blocking IL-13, Lebrikizumab-Lbkz helps to decrease swelling and irritation in the skin.

The recommended dose of Lebrikizumab-Lbkz is 500 mg (two 250 mg injections) at Week 0 and Week 2, followed by 250 mg (one injection) every 2 weeks until Week 16 or later, when adequate clinical response is achieved. The maintenance dose is 250 mg every 4 weeks.

Lebrikizumab-Lbkz is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

• Prior serious hypersensitivity to Lebrikizumab-Lbkz or any excipients in the product

Common side effects of Lebrikizumab-Lbkz:

• Pink eye
• Injection site reactions
• Herpes zoster (shingles)

Serious side effects are rare with Lebrikizumab-Lbkz. Contact your healthcare provider immediately if you experience any of the following:

• Allergic reaction: breathing problems; swelling of the face, lips, mouth, tongue, or throat; hives; itching; stomach cramps; dizziness
• Eye problems: eye pain, changes in vision, blurred vision

There are no major drug interactions listed for this medication. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Various FDA-approved generic manufacturers

It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.

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