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Intelence is the brand name for etravirine and is available as an oral tablet.

Intelence is available as a 25 mg, 100 mg, and 200 mg oral tablet.

Intelence is a HIV ARV and is used to treat HIV infection in people 2 years of age and older.

Intelence is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It blocks an enzyme found in HIV called reverse transcriptase that usually helps the virus make copies of itself. By blocking reverse transcriptase, Intelence prevents the HIV virus from doing so and from spreading.

Intelence is dosed as follows:

• Adults: The typical dose is 200 mg by mouth twice daily after a meal
• Children age 2 years and older who weigh at least 22 lbs: The dose will depend on your child’s weight. The typical dose ranges from 100 mg to 200 mg by mouth twice daily after a meal

Intelence is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Intelence:

• Higher fat levels in the blood
• Higher blood sugar levels
• Rash
• Higher creatine kinase levels in the blood
• Abnormal liver lab results
• Nerve pain or tingling sensation in hands or feet

Serious side effects are rare with Intelence. Contact your healthcare provider immediately if you experience any of the following.

• Severe allergic reactions: fever, rash, general discomfort, muscle or joint pain, mouth sores, blisters, facial swelling
• Liver injury: nausea, vomiting, not feeling hungry, pain in the right side of the stomach, yellowing of the whites of the eyes or skin, dark-colored urine, light-colored stool

The following medications may interact with Intelence:

• Co-administration of Intelence with other drugs can alter the concentrations of other drugs and other drugs may alter the concentrations of etravirine. The potential drug-drug interactions must be considered prior to and during therapy

Janssen Pharmaceuticals

It is not known if Intelence can harm your unborn baby. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. There is a pregnancy exposure registry that monitors pregnancy outcomes in individuals exposed to Intelence during pregnancy. Healthcare providers are encouraged to register patients by calling the Antiretroviral Pregnancy Registry (APR) at 1-800-258-4263.

• Etravirine