Key facts about Imlunestrant
What dosages is Imlunestrant available in?
Imlunestrant is available as a 200 mg oral tablet.
What is Imlunestrant used for?
Imlunestrant is an estrogen receptor antagonist used in the treatment of adults with ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.
How does Imlunestrant work?
Imlunestrant works by blocking and breaking down overactive estrogen receptors that help some breast cancers grow. This can slow the cancer’s progression.
How do I take Imlunestrant?
The recommended dosage is 400 mg orally once daily, on an empty stomach.
Is it safe for me to take Imlunestrant?
Imlunestrant is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Imlunestrant Common Side Effects
Common side effects of Imlunestrant:
- Musculoskeletal pain (muscle or joint pain)
- Fatigue
- Diarrhea
- Nausea
- Constipation
- Abdominal pain
- Laboratory abnormalities: decreased hemoglobin (anemia), decreased calcium, decreased neutrophils (a type of white blood cell), increased AST and ALT (liver enzymes), increased triglycerides, decreased platelets, and increased cholesterol
Imlunestrant Serious Side Effects
Serious side effects are rare with Imlunestrant. Contact your healthcare provider immediately if you experience any of the following:
- Serious allergic reaction: hives; rash, swelling of the face, tongue, or around the eyes, trouble breathing; wheezing, trouble swallowing
Effects of other drugs, drug classes and over-the-counter products on Imlunestrant
The following medications may interact with Imlunestrant:
- Strong CYP3A inhibitors and inducers
Who makes Imlunestrant?
Various FDA-approved generic manufacturers
Is Imlunestrant safe in pregnancy?
Imlunestrant can cause harm to your unborn baby. You should take a pregnancy tess before starting treatment. Females that can become pregnant should use effective contraception during treatment and for 1 week after the last dose. Males with female partners that can become pregnant should also use effective contraception during treatment and for 1 week after the last dose.
