Key facts about Imipenem/Cilastatin/Relebactam
What dosages is Imipenem/Cilastatin/Relebactam available in?
Imipenem/Cilastatin/Relebactam is available as an IV injection that contains imipenem 500 mg (anhydrate equivalent), cilastatin 500 mg (free acid equivalent), and relebactam 250 mg (anhydrate equivalent).
What is Imipenem/Cilastatin/Relebactam used for?
Imipenem/Cilastatin/Relebactam is part of the penem antibiotic /beta lactamase inhibitor/renal dehydropeptidase inhibitor combinations class and treats urinary tract infection, bacterial infection, and gastrointestinal infection.
How does Imipenem/Cilastatin/Relebactam work?
Imipenem/Cilastatin/Relebactam is an antibiotic and is typically used in adults for treating serious infections including pneumonia that develops from the hospital or ventilator, complicated urinary tract infections (UTIs), and 3) complicated stomach infections.
How do I take Imipenem/Cilastatin/Relebactam?
Imipenem/Cilastatin/Relebactam is injected into your veins. It’s typically given to people in the hospital by a healthcare provider. But, depending on the infection, some people might be able to take Imipenem/Cilastatin/Relebactam at home under instructions from their provider.
Is it safe for me to take Imipenem/Cilastatin/Relebactam?
Imipenem/Cilastatin/Relebactam is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Imipenem/Cilastatin/Relebactam is contraindicated in patients with a history of known
severe hypersensitivity to any component of Imipenem/Cilastatin/Relebactam.
Imipenem/Cilastatin/Relebactam Common Side Effects
Common side effects of Imipenem/Cilastatin/Relebactam:
- Increase in liver enzymes
- Anemia
- Diarrhea
- Low potassium blood levels
- Low sodium blood levels
Imipenem/Cilastatin/Relebactam Serious Side Effects
Serious side effects are rare with Imipenem/Cilastatin/Relebactam. Contact your doctor if you experience any of the following:
- Serious Allergic Reactions
- Seizures and Central Nervous System Reactions
- Potentially Serious Diarrhea
- Antibacterial Resistance
Effects of other drugs, drug classes and over-the-counter products on Imipenem/Cilastatin/Relebactam
The following medications may interact with Imipenem/Cilastatin/Relebactam:
- Ganciclovir: Avoid concomitant use
- Valproic Acid or Divalproex Sodium: Avoid concomitant use
Who makes Imipenem/Cilastatin/Relebactam?
Various FDA-approved generic manufacturers
Is Imipenem/Cilastatin/Relebactam safe in pregnancy?
Based on animal data, Imipenem/Cilastatin/Relebactam may cause fetal harm when administered to pregnant individuals. It should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.
