Used for Hypertension

View HYZAAR savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or HYZAAR Patient Assistance Program.

Programs are suitable for individuals who want to buy HYZAAR without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by Merck & Co., Inc.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about HYZAAR

What is HYZAAR?

What is HYZAAR?

HYZAAR is the brand name for losartan/hydrochlorothiazide and is available as an oral tablet.

What dosages is HYZAAR available in?

What dosages is HYZAAR available in?

HYZAAR (losartan/hydrochlorothiazide) is available as an oral tablet that is available in strengths of 50 mg/12.5 mg, 100 mg/12.5 mg, and 100 mg/25 mg.

What is HYZAAR used for?

What is HYZAAR used for?

HYZAAR is an ARB/diuretic (water pill) combo used to treat high blood pressure and to lower the risk of stroke in people with high blood pressure and an enlarged left ventricle of the heart.

How does HYZAAR work?

How does HYZAAR work?

HYZAAR is a combination of two medications that work together to lower blood pressure:

1. Losartan is an angiotensin II receptor blocker (ARB). It works by blocking angiotensin II, a hormone that raises your blood pressure, from attaching to its receptors (signaling proteins). In doing so, losartan lowers your blood pressure by relaxing the blood vessels
2. Hydrochlorothiazide is a thiazide diuretic (water pill). It works in your kidneys to remove extra water and certain electrolytes (like sodium and potassium). This helps lower blood pressure

How do I take HYZAAR?

How do I take HYZAAR?

HYZAAR is typically taken by mouth once daily. Your provider will adjust your dose based on how well it’s helping your blood pressure and if you’re having side effects.

Is it safe for me to take HYZAAR?

Is it safe for me to take HYZAAR?

HYZAAR is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have anuria or have diabetes and are taking aliskiren.

HYZAAR Common Side Effects

HYZAAR Common Side Effects

Common side effects of HYZAAR include:

  • Upper respiratory tract infection (i.e., common cold)
  • Dizziness
  • Back pain
  • Headache
  • Trouble sleeping
  • Rash
  • Stomach upset
HYZAAR Serious Side Effects

HYZAAR Serious Side Effects

Serious side effects are rare with HYZAAR. Contact your healthcare provider immediately if you experience any of the following.

  • Dangerously low blood pressure: dizziness, lightheadedness, pale skin, feeling faint
  • Serious kidney problems: urinating less often than usual, swelling in your feet, ankles, or hands, unexplained weight gain
  • High blood potassium levels: nausea, muscle weakness, abnormal heartbeat
  • Severe allergic reaction: swelling of your lips, tongue, throat, or face, trouble breathing, rash
Effects of other drugs, drug classes and over-the-counter products on HYZAAR

Effects of other drugs, drug classes and over-the-counter products on HYZAAR

The following medications may interact with HYZAAR:

  • Cholestyramine and colestipol – Reduced absorption of thiazides
  • Agents increasing serum potassium – Risk of hyperkalemia.
  • Lithium – Risk of lithium toxicity
  • NSAIDs – Increased risk of renal impairment and reduced diuretic, natriuretic, and antihypertensive effects
  • Dual inhibition of the renin-angiotensin system – Increased risk of renal impairment, hypotension, syncope, and hyperkalemia
Who makes HYZAAR?

Who makes HYZAAR?

Merck & Co., Inc.

Is HYZAAR safe in pregnancy?

Is HYZAAR safe in pregnancy?

HYZAAR may cause harm to your unborn baby. You should discontinue this medication immediately if you become pregnant.


What to do if you missed your HYZAAR dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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